CAJ | 학술논문

目的：观察奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的临床疗效。方法将肝硬化合并上消化道出血患者46例随机分为观察组及对照组，各23例。均给予常规治疗及奥美拉唑治疗，观察组患者在此基础上加用奥曲肽和凝血酶，两组均治疗3 d后观察临床效果。结果观察组总有效率91．3％，高于对照组的56．5％（ P ＜0．01）。观察组患者输血量少于对照组（ P ＜0．01）；观察组止血时间及住院时间均短于对照组（ P ＜0．01）。结论奥曲肽联合凝血酶治疗肝硬化合并上消化道出血疗效显著，可有效减少患者上消化道出血量，改善患者临床症状。
목적：관찰오곡태연합응혈매치료간경화합병상소화도출혈적림상료효。방법장간경화합병상소화도출혈환자46례수궤분위관찰조급대조조，각23례。균급여상규치료급오미랍서치료，관찰조환자재차기출상가용오곡태화응혈매，량조균치료3 d후관찰림상효과。결과관찰조총유효솔91．3％，고우대조조적56．5％（ P ＜0．01）。관찰조환자수혈량소우대조조（ P ＜0．01）；관찰조지혈시간급주원시간균단우대조조（ P ＜0．01）。결론오곡태연합응혈매치료간경화합병상소화도출혈료효현저，가유효감소환자상소화도출혈량，개선환자림상증상。
Objective To observe the clinical effect of combination of octreotide and thrombin in the treatment of cirrhosis with upper gastrointestinal bleeding .Methods Forty-six cirrhosis patients with upper gastrointestinal bleeding were analyzed and divid -ed into two groups .All the patients received conventional and omeprazole treatment .The observation group received combination treat-ment of octreotide and thrombin on the basis of conventional and omeprazole treatment .Clinical effect was observed 3 days after treat-ment.Resutls The total efficiency rate of observation group was 91.3%,higher than 56.5 %of control group( P <0.01).The blood transfusion,bleeding time and length of stay of observation group were lower than that of control group ( P <0.01).Conclusi on Com-bination of octreotide and thrombin in the treatment of cirrhosis patients with upper gastrointestinal bleeding can effectively reduce the volume of gastrointestinal bleeding and improve clinical symptoms .