中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
CHINESE JOURNAL OF EVIDENCE-BASES CARDIOVASCULAR MEDICINE
2014年
2期
187-189
,共3页
李景莎%钟敬泉%齐书英%王冬梅
李景莎%鐘敬泉%齊書英%王鼕梅
리경사%종경천%제서영%왕동매
孤立性房颤%危险因素
孤立性房顫%危險因素
고립성방전%위험인소
Lone atrial fibrillation%Risk factors
目的:探讨孤立性心房(LAF)颤动(房颤)患者的相关危险因素。方法纳入2011年1月~2012年6月间行射频消融术治疗孤立性房颤患者14例,将同期行射频消融术治疗单纯室上性心动过速(PSVT)的患者43例作为对照组。收集两组病例的一般临床资料,并对年龄、血压、心率、左房大小(LA)、体重指数(BMI)及血脂、血糖等生化指标进行分析。结果与对照组比较,LAF组患者左房较大[(35.93±5.74)mm vs.(31.20±4.64)mm,P=0.007],体重指数(BMI;25.70±3.21 vs.23.49±2.32, P=0.003)、低密度脂蛋白胆固醇[LDL-C;(2.85±0.61)mmol/L vs.(2.23±0.31)mmol/L,P=0.038]及空腹血糖[Glu;(5.96±1.64)mmol/L vs.((4.76±0.74)mmol/L,P=0.031]均较高,而高密度脂蛋白胆固醇较低[HDL-C;(1.14±0.21)mmol/L vs.(1.49±0.27)mmol/L,P=0.015],总胆固醇及甘油三脂两组比较无明显差异(P>0.05)。LA与BMI(r=0.55,P<0.05)、LDL-C(r=0.85,P<0.01)、Glu(r=0.81, P<0.01)呈正相关,与HDL-C呈负相关(r=-0.91,P<0.01)。结论 LAF在临床上并非孤立,LA、BMI、血糖、血脂均可能为孤立性房颤的相关危险因素。
目的:探討孤立性心房(LAF)顫動(房顫)患者的相關危險因素。方法納入2011年1月~2012年6月間行射頻消融術治療孤立性房顫患者14例,將同期行射頻消融術治療單純室上性心動過速(PSVT)的患者43例作為對照組。收集兩組病例的一般臨床資料,併對年齡、血壓、心率、左房大小(LA)、體重指數(BMI)及血脂、血糖等生化指標進行分析。結果與對照組比較,LAF組患者左房較大[(35.93±5.74)mm vs.(31.20±4.64)mm,P=0.007],體重指數(BMI;25.70±3.21 vs.23.49±2.32, P=0.003)、低密度脂蛋白膽固醇[LDL-C;(2.85±0.61)mmol/L vs.(2.23±0.31)mmol/L,P=0.038]及空腹血糖[Glu;(5.96±1.64)mmol/L vs.((4.76±0.74)mmol/L,P=0.031]均較高,而高密度脂蛋白膽固醇較低[HDL-C;(1.14±0.21)mmol/L vs.(1.49±0.27)mmol/L,P=0.015],總膽固醇及甘油三脂兩組比較無明顯差異(P>0.05)。LA與BMI(r=0.55,P<0.05)、LDL-C(r=0.85,P<0.01)、Glu(r=0.81, P<0.01)呈正相關,與HDL-C呈負相關(r=-0.91,P<0.01)。結論 LAF在臨床上併非孤立,LA、BMI、血糖、血脂均可能為孤立性房顫的相關危險因素。
목적:탐토고립성심방(LAF)전동(방전)환자적상관위험인소。방법납입2011년1월~2012년6월간행사빈소융술치료고립성방전환자14례,장동기행사빈소융술치료단순실상성심동과속(PSVT)적환자43례작위대조조。수집량조병례적일반림상자료,병대년령、혈압、심솔、좌방대소(LA)、체중지수(BMI)급혈지、혈당등생화지표진행분석。결과여대조조비교,LAF조환자좌방교대[(35.93±5.74)mm vs.(31.20±4.64)mm,P=0.007],체중지수(BMI;25.70±3.21 vs.23.49±2.32, P=0.003)、저밀도지단백담고순[LDL-C;(2.85±0.61)mmol/L vs.(2.23±0.31)mmol/L,P=0.038]급공복혈당[Glu;(5.96±1.64)mmol/L vs.((4.76±0.74)mmol/L,P=0.031]균교고,이고밀도지단백담고순교저[HDL-C;(1.14±0.21)mmol/L vs.(1.49±0.27)mmol/L,P=0.015],총담고순급감유삼지량조비교무명현차이(P>0.05)。LA여BMI(r=0.55,P<0.05)、LDL-C(r=0.85,P<0.01)、Glu(r=0.81, P<0.01)정정상관,여HDL-C정부상관(r=-0.91,P<0.01)。결론 LAF재림상상병비고립,LA、BMI、혈당、혈지균가능위고립성방전적상관위험인소。
Objective To investigate the relative risk factors in patients with lone atrial fibrillation (LAF). Methods The patients with LAF treated with radiofrequency ablation (RFA) were chosen as LAF group (n=14), and patients with paroxysmal supraventricular tachycardia (PSVT) treated with RFA at the same time were chosen as control group (n=43) from Jan. 2011 to Jun. 2012. The general clinical data was collected from the patients in two groups, and the changes of age, blood pressure (BP), heart rate (HR), left atrial size, BMI, blood fat and plasma glucose were analyzed. Results Compared with control group, in LAF group left atrial size was largger [(35.93± 5.74) mm vs. (31.20±4.64) mm, P=0.007], levels of BMI (25.70±3.21 vs. 23.49±2.32, P=0.003), LDL-C [(2.85± 0.61) mmol/L vs. (2.23±0.31) mmol/L, P=0.038] and FBG [(5.96±1.64) mmol/L vs. (4.76±0.74) mmol/L, P=0.031] were higher, level of HDL-C [(1.14±0.21) mmol/L vs. (1.49±0.27) mmol/L, P=0.015] was lower, and TC and TG had no significant changes (P>0.05). The left atrial size was positively correlated to BMI (r=0.55, P<0.05), LDL-C(r=0.85, P<0.01) and FBG (r=0.81, P<0.01), and negatively correlated to HDL-C (r=-0.91, P<0.01). Conclusion LAF is not isolated in clinic, and left atrial size, BMI, blood fat and plasma glucose are its relative risk factors.