CAJ | 학술논문

IgG4相关性疾病（IgG4-RD）是新近被认识和关注的一类疾病。该类疾病以血清IgG4水平升高以及 IgG4阳性浆细胞浸润多种器官和组织为特征，常见受累器官包括胰腺、泪腺、唾液腺、后腹膜、胆道、肾脏、甲状腺及垂体等，累及的器官或组织由于慢性炎症及纤维化进程可导致弥漫性肿大。IgG4-RD 作为一种新的临床疾病逐渐被广泛认识，但国内报道仍较少。该文报道1例IgG4-RD 患者的诊治经过，为临床医生认识、诊治该疾病提供参考。
IgG4상관성질병（IgG4-RD）시신근피인식화관주적일류질병。해류질병이혈청IgG4수평승고이급 IgG4양성장세포침윤다충기관화조직위특정，상견수루기관포괄이선、루선、타액선、후복막、담도、신장、갑상선급수체등，루급적기관혹조직유우만성염증급섬유화진정가도치미만성종대。IgG4-RD 작위일충신적림상질병축점피엄범인식，단국내보도잉교소。해문보도1례IgG4-RD 환자적진치경과，위림상의생인식、진치해질병제공삼고。
IgG4-related disease is a newly recognized clinicopathological entity characterized by in-creased serum IgG4 and abundant IgG4-bearing plasma cell infiltration involving a variety of organs and tissues. The most commonly involved organs or tissues include the pancreas,lacrimal gland,salivary glands,retroper-itoneal space,biliary tract,kidney,thyroid and pituitary,etc,presenting with diffuse swelling induced by chronic inflammation accompanied with progressive fibrosis.In this article,we reported the diagnosis and treatment of one case of IgG4-related disease that was effectively treated with disease-modifying anti-rheumatic drugs (DMARDs),providing physicians with deep understanding and clinical evidence of IgG4-related dis-ease.