CAJ | 학술논문

目的：探讨肝细胞癌根治术后行辅助性肝动脉化疗栓塞对患者复发率的影响。方法对2006~2008年本院行肝癌切除术后的112例患者，按术后2个月内是否进行辅助性肝动脉化疗栓塞分为观察组（64例）和对照组（48例），对比分析两组患者术后1、2、3、4、5年的累积复发率和生存率。结果观察组1、2、3、4、5年的累积复发率分别为10.9%、44.3%、59.4%、85.6%、96.2%；对照组1、2、3、4、5年的累积复发率分别为45.8%、63.4%、80.5%、90.2%、97.3%。两组间比较术后1、2、3年差异有统计学意义（P＜0.05）；术后4、5年差异无统计学意义（P＞0.05）。结论肝细胞癌根治术后行辅助性肝动脉化疗栓塞可明显降低患者前期复发率，对后期复发率无明显作用。
목적：탐토간세포암근치술후행보조성간동맥화료전새대환자복발솔적영향。방법대2006~2008년본원행간암절제술후적112례환자，안술후2개월내시부진행보조성간동맥화료전새분위관찰조（64례）화대조조（48례），대비분석량조환자술후1、2、3、4、5년적루적복발솔화생존솔。결과관찰조1、2、3、4、5년적루적복발솔분별위10.9%、44.3%、59.4%、85.6%、96.2%；대조조1、2、3、4、5년적루적복발솔분별위45.8%、63.4%、80.5%、90.2%、97.3%。량조간비교술후1、2、3년차이유통계학의의（P＜0.05）；술후4、5년차이무통계학의의（P＞0.05）。결론간세포암근치술후행보조성간동맥화료전새가명현강저환자전기복발솔，대후기복발솔무명현작용。
Objective To analyze the effect of postoperative adjuvant transarterial chemoembolization upon recurrence after radical resection of hepatocellular carcinoma. Methods 112 patients after radical resection of hepatocellular carcinoma were divided into objective group(64 cases) and control group(48 cases). The objective group was treated with postoperative adjuvant transarterial chemoembolization after the operation. The difference of recurrence rate between the two groups were compared. Results The recurrence rate of the objective group was 10.9%, 44.3%, 59.4%, 85.6%, 96.2%respectively at the time of first to fifth year after the operation. The recurrence rate of the control group was 45.8%, 63.4%, 80.5%, 90.2%, 97.3%respectively. There were significant differences in the data of the recurrence rate in the first to the third year. Conclusion It would get a satisfactory effect to use postoperative adjuvant transarterial chemoembolization after radical resection of hepatocellular carcinoma for reducing the recurrence rate.