中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
2期
61-63
,共3页
早产儿视网膜病变%胎龄%出生体重%影响因素
早產兒視網膜病變%胎齡%齣生體重%影響因素
조산인시망막병변%태령%출생체중%영향인소
Retinopathy of prematurity%Gestational age%Birth weight%Influencing factors
目的：筛查早产儿视网膜病变情况以及分析影响早产儿视网膜病变的危险因素。方法选取2011年10月~2012年10月期间在我院分娩的胎龄小于36周早产儿515例作为研究对象。对早产儿进行眼部筛查，是否有视网膜病变的情况。根据早产儿的性别、胎龄、出生体重、贫血、酸中毒、低血糖血症、吸氧、肺炎以及输血史等因素进行单因素和多因素Logistic回归分析。结果515例早产儿眼部检查发现82例出现视网膜病变，病变率为15.9%，经过视网膜激光光凝术治疗后80例手术成功，随访半年，病情得到很好的控制。单因素分析结果显示，胎龄、出生体重、肺炎、吸氧、低血糖血症、贫血以及输血史是影响早产儿视网膜病变的主要因素。经过多因素Logistic回归分析最终结果分析，早产儿出生体重和吸氧是影响其视网膜病变的关键因素，其他因素无统计学意义。结论早产儿出生体重以及吸氧是影响视网膜病变的主要因素，早期筛查发现及时治疗，可以有效控制病情，降低早产儿的致盲率。
目的：篩查早產兒視網膜病變情況以及分析影響早產兒視網膜病變的危險因素。方法選取2011年10月~2012年10月期間在我院分娩的胎齡小于36週早產兒515例作為研究對象。對早產兒進行眼部篩查，是否有視網膜病變的情況。根據早產兒的性彆、胎齡、齣生體重、貧血、痠中毒、低血糖血癥、吸氧、肺炎以及輸血史等因素進行單因素和多因素Logistic迴歸分析。結果515例早產兒眼部檢查髮現82例齣現視網膜病變，病變率為15.9%，經過視網膜激光光凝術治療後80例手術成功，隨訪半年，病情得到很好的控製。單因素分析結果顯示，胎齡、齣生體重、肺炎、吸氧、低血糖血癥、貧血以及輸血史是影響早產兒視網膜病變的主要因素。經過多因素Logistic迴歸分析最終結果分析，早產兒齣生體重和吸氧是影響其視網膜病變的關鍵因素，其他因素無統計學意義。結論早產兒齣生體重以及吸氧是影響視網膜病變的主要因素，早期篩查髮現及時治療，可以有效控製病情，降低早產兒的緻盲率。
목적：사사조산인시망막병변정황이급분석영향조산인시망막병변적위험인소。방법선취2011년10월~2012년10월기간재아원분면적태령소우36주조산인515례작위연구대상。대조산인진행안부사사，시부유시망막병변적정황。근거조산인적성별、태령、출생체중、빈혈、산중독、저혈당혈증、흡양、폐염이급수혈사등인소진행단인소화다인소Logistic회귀분석。결과515례조산인안부검사발현82례출현시망막병변，병변솔위15.9%，경과시망막격광광응술치료후80례수술성공，수방반년，병정득도흔호적공제。단인소분석결과현시，태령、출생체중、폐염、흡양、저혈당혈증、빈혈이급수혈사시영향조산인시망막병변적주요인소。경과다인소Logistic회귀분석최종결과분석，조산인출생체중화흡양시영향기시망막병변적관건인소，기타인소무통계학의의。결론조산인출생체중이급흡양시영향시망막병변적주요인소，조기사사발현급시치료，가이유효공제병정，강저조산인적치맹솔。
Objective To screen for retinopathy of prematurity and identify the risk factors related to the retinopathy of prematurity. Methods A total of 515 premature infants with a gestational age of less than 36 weeks who were delivered in our hospital from October 2011 to October 2012 were screened for retinopathy. Factors were analyzed by univarite and multivariate Logistics regression analysis, such as the premature infants' sex, gestational age, birth weight, anemia, acidosis, hypoglycemia, oxygen inhalation, pneumonia, blood infusion. Results The screening test showed that 82 of 515 premature infants had retinopathy and the morbidity was 15.9%. Eighty cases of retinopathy of prematurity were treated after retinal laser photocoagulation and followed up for half a year with a good condition. Univariate analysis result showed that gestational age, birth weight, pneumonia, oxygen inhalation, hypoglycemia, anemia, blood infusion were the major risk factors related to retinopathy in premature infants. Multivariate analysis result showed that birth weight and oxygen inhalation were the key factors relative to retinopathy of prematurity. Conclusion Birth weight and oxygen inhalation of premature infants are the key factors related to retinopathy. Early screening, diagnosis and treatment can effectively control the progression and decrease the rate of blindness in premature infants.
