CAJ | 학술논문

目的：探讨老老年患者骨质疏松症与心血管疾病危险因素的相关性。方法选取2008年1月至2012年7月广州市第一人民医院老年病科住院的≥75岁的患者1073例，根据骨密度结果分为骨质疏松组及骨量正常组，并记录其合并的心血管疾病情况及危险因素。结果骨质疏松组中，冠心病、高血脂、糖尿病及吸烟所占的比例高于骨量正常组，两组比较差异有统计学意义（P＜0.05）。多因素Logistic回归分析结果显示，同型半胱氨酸、低密度脂蛋白、胆固醇为老年骨质疏松患者的主要危险因素，HDL、体重为老年骨质疏松患者的保护因素。女性、高血压、冠心病、高脂血症、糖尿病均为老年骨质疏松主要危险合并症。结论老老年骨质疏松症是一个全身性疾病，与冠心病、高脂血症等心血管疾病及危险因素密切相关，应全面治疗及预防。
목적：탐토로노년환자골질소송증여심혈관질병위험인소적상관성。방법선취2008년1월지2012년7월엄주시제일인민의원노년병과주원적≥75세적환자1073례，근거골밀도결과분위골질소송조급골량정상조，병기록기합병적심혈관질병정황급위험인소。결과골질소송조중，관심병、고혈지、당뇨병급흡연소점적비례고우골량정상조，량조비교차이유통계학의의（P＜0.05）。다인소Logistic회귀분석결과현시，동형반광안산、저밀도지단백、담고순위노년골질소송환자적주요위험인소，HDL、체중위노년골질소송환자적보호인소。녀성、고혈압、관심병、고지혈증、당뇨병균위노년골질소송주요위험합병증。결론로노년골질소송증시일개전신성질병，여관심병、고지혈증등심혈관질병급위험인소밀절상관，응전면치료급예방。
Objective To study the correlation between osteoporosis and the risk factors of cardiovascular diseases in the elderly. Methods One thousand and seventy-three patients, who were hospitalized in the Department of Geriatrics in Guangzhou First People’s Hospital, from January 2008 to July 2012, with the age over 75 years old, were selected.All the patients were divided into osteoporosis group and normal bone mass group according to their bone mineral density.The combined cardiovascular diseases and the related risk factors were recorded.Results The proportion of patients with coronary heart diseases, hyperlipidemia, diabetic mellitus, and smoking in osteoporosis group was significantly higher than that in normal bone mass group (P<0.05). Multivariate logistic regression analysis showed that HCY, LDL, and TC were the major risk factors of osteoporosis in the elderly. HDL and body weight were protective factors.Female, hypertension, coronary heart diseases, hyperlipidemia, and diabetes mellitus were the main risk factors of complication in the elderly patients with osteoporosis.Conclusion Senile osteoporosis is a systematic disease, which is closely correlated with cardiovascular disease-related risk factors including coronary heart disease and hyperlipidemia, and should be treated and prevented comprehensively.