临床药物治疗杂志
臨床藥物治療雜誌
림상약물치료잡지
CLINICAL MEDICATION JOURNAL
2014年
2期
14-18
,共5页
妊娠期%视神经脊髓炎%治疗
妊娠期%視神經脊髓炎%治療
임신기%시신경척수염%치료
Pregnancy%Neuromyelitis optic%Treatment
目的：分析妊娠期对视神经脊髓炎的影响和治疗选择。方法：总结分析近年来妊娠期对视神经脊髓炎的影响和治疗选择的文章。结果和结论：视神经脊髓炎是一种中枢神经系统慢性自身免疫性疾病，主要发生在生育期女性。妊娠可以触发疾病发生或加重病情，疾病可以增加产科并发症风险，但绝大多数妊娠获得成功结果。妊娠期病情波动可以采用静脉大剂量甲基泼尼龙、免疫球蛋白、血浆交换等治疗，以及激素联合免疫球蛋白或血浆交换治疗。病情缓解至少半年后妊娠或许有利于母婴健康，分娩后恢复维持治疗有助于预防疾病复发。
目的：分析妊娠期對視神經脊髓炎的影響和治療選擇。方法：總結分析近年來妊娠期對視神經脊髓炎的影響和治療選擇的文章。結果和結論：視神經脊髓炎是一種中樞神經繫統慢性自身免疫性疾病，主要髮生在生育期女性。妊娠可以觸髮疾病髮生或加重病情，疾病可以增加產科併髮癥風險，但絕大多數妊娠穫得成功結果。妊娠期病情波動可以採用靜脈大劑量甲基潑尼龍、免疫毬蛋白、血漿交換等治療，以及激素聯閤免疫毬蛋白或血漿交換治療。病情緩解至少半年後妊娠或許有利于母嬰健康，分娩後恢複維持治療有助于預防疾病複髮。
목적：분석임신기대시신경척수염적영향화치료선택。방법：총결분석근년래임신기대시신경척수염적영향화치료선택적문장。결과화결론：시신경척수염시일충중추신경계통만성자신면역성질병，주요발생재생육기녀성。임신가이촉발질병발생혹가중병정，질병가이증가산과병발증풍험，단절대다수임신획득성공결과。임신기병정파동가이채용정맥대제량갑기발니룡、면역구단백、혈장교환등치료，이급격소연합면역구단백혹혈장교환치료。병정완해지소반년후임신혹허유리우모영건강，분면후회복유지치료유조우예방질병복발。
Objective: To analyze effect of pregnancy on neuromyelitis optic and its option of treatments. Methods:We col ected and analyzed publications on neuromyelitis optic of pregnancy and its options of treatments. Results and Comclusion:Neuromyelitis optic is a chronic, autoimmune disease of the central nervous system that predominantly occurs in women of childbearing age. Pregnancy may trigger and exacerbate the disease. The disease may increase the risk of obstetric complications. However, the majority of pregnancies end in success. The lfares of neuromyelitis optic associated with pregnancy can be treated by high-dose intravenous methylprednisolone, immunoglobulin, plasma exchange, and the combination of steroid and immunoglobulin, or plasma exchange. The remission of disease at least six months before conception may be better for both mother and child. Maternal health and fetal development should be closely monitored by both obstetrician and neurologist during pregnancy. The restoration treatment in postpartum helps protect against the relapse.
