CAJ | 학술논문

目的：综述晚期乳腺癌药物研究与治疗进展。方法：收集相关最新发表的文章，对晚期乳腺癌药物和治疗进展进行分析总结。结果与结论：晚期乳腺癌属于不可治愈的疾病。临床实践证明，以紫杉类药物、曲妥珠单抗、第三代芳香化酶抑制剂等为新一代抗癌新药应用于临床，显著改善患者的生存和生活质量，晚期乳腺癌逐渐演变成为一种慢性病。近年来，一些具有全新作用机制的新型抗肿瘤药物如帕妥珠单抗、曲妥珠单抗emtansine、氟维司群注射液、依维莫司等的出现，将改变晚期乳腺癌的治疗策略。
목적：종술만기유선암약물연구여치료진전。방법：수집상관최신발표적문장，대만기유선암약물화치료진전진행분석총결。결과여결론：만기유선암속우불가치유적질병。림상실천증명，이자삼류약물、곡타주단항、제삼대방향화매억제제등위신일대항암신약응용우림상，현저개선환자적생존화생활질량，만기유선암축점연변성위일충만성병。근년래，일사구유전신작용궤제적신형항종류약물여파타주단항、곡타주단항emtansine、불유사군주사액、의유막사등적출현，장개변만기유선암적치료책략。
Objective:To review the recent advances in the treatment of advanced breast cancer and drug research. Methods: We collected the latest research related to the treatment of advanced breast cancer and drugs, then give the analysis and summary. Results and conclusion: Metastatic breast cancer currently has no cure, fortunately,a new generation of antitumor-drug were available in clinical application, such as taxanes, trastuzumab and the third generation of aromatase inhibitors, then the survival and quality of life of patients was signiifcantly improved . Clinical practice has proved that metastatic breast cancer gradually evolved into a chronic disease. In recent years, some new mechanisms antitumor drugs such as Pertuzumab,T-DM1,Fulvestrant and Everolimus, etc, wil change the strategy of metastatic breast cancer.