CAJ | 학술논문

帕金森病是一种由于黑质的多巴胺细胞变性导致的一种神经系统退行性疾病。临床典型症状包括静止性震颤、运动迟缓、肌强直和姿势障碍。然而，帕金森病的早期阶段症状并不典型。因此发展一种早期诊断帕金森病的手段是非常必要的。经颅彩色多普勒超声作为一种非侵入性的技术，已成为帕金森病的诊断及与帕金森综合征鉴别诊断的重要工具。最重要的是，经颅彩色多普勒超声不仅能够探测黑质的高回声，同时能够检测到血管的狭窄程度，是早期诊断帕金森病及能够鉴别诊断血管性帕金森综合征的关键。
파금삼병시일충유우흑질적다파알세포변성도치적일충신경계통퇴행성질병。림상전형증상포괄정지성진전、운동지완、기강직화자세장애。연이，파금삼병적조기계단증상병불전형。인차발전일충조기진단파금삼병적수단시비상필요적。경로채색다보륵초성작위일충비침입성적기술，이성위파금삼병적진단급여파금삼종합정감별진단적중요공구。최중요적시，경로채색다보륵초성불부능구탐측흑질적고회성，동시능구검측도혈관적협착정도，시조기진단파금삼병급능구감별진단혈관성파금삼종합정적관건。
Parkinson's disease is a progressive neurological disorder, which results from the degeneration of dopamine-producing cells in the substantia nigra (SN). Clinical symptoms typically include static tremor, bradykinesia, myotonia, and postural instability. However, clinical features in the early stages of Parkinson's disease are atypical. Therefore, it is important to develop a diagnostic tool aimed to recognize the early stages of Parkinson's disease. Transcranial color-coded sonography as a non-invasive technology has become an important instrument in the diagnosis of Parkinson's disease and in the differential diagnosis of Parkinsonism. Above all, transcranial color-coded sonography has the capability of detecting substantia nigra hyperechogenicity and shows stenosis of vessels, which plays an important role in diagonosing Parkinson's disease in its early stages and differentiating Parkinson's disease and vascular parkinsonism. The main purpose of the current article is to summarize the significance of transcranial color-coded sonography in the diagnosis and differential diagnosis of Parkinson's disease.