中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
3期
279-281
,共3页
银屑病%男性%骨代谢
銀屑病%男性%骨代謝
은설병%남성%골대사
Psoriasis%Male%Bone metabolism
目的：本研究旨在通过对男性银屑病患者代谢的影响因素的分析，探讨骨质疏松与银屑病的关系，为进一步预防及治疗提供依据。方法本组61例明确诊断的男性银屑病患者均来自我院皮肤科门诊，同时根据年龄、体重指数、族别选择61例同期在我院体检中心体检的男性志愿者进行配对研究。记录并分析了患者静脉血测定血清钙、磷、碱性磷酸酶，并进行骨密度测定。结果两组钙、磷及碱性磷酸酶水平无明显差异，银屑病组血清钙略低于对照组，但无统计学差异，而血清磷水平平均差异不显著；2组腰椎及股骨颈骨密度比较，银屑病组均低于对照组，且有统计学意义；进一步分析发现银屑病组股骨颈骨密度下降较明显，其差异具有统计学意义。股骨颈骨密度值比较，银屑病组无论是骨量减低还是骨质疏松患者比例明显高于非银屑病组。结论男性银屑病患者骨代谢水平明显下降。
目的：本研究旨在通過對男性銀屑病患者代謝的影響因素的分析，探討骨質疏鬆與銀屑病的關繫，為進一步預防及治療提供依據。方法本組61例明確診斷的男性銀屑病患者均來自我院皮膚科門診，同時根據年齡、體重指數、族彆選擇61例同期在我院體檢中心體檢的男性誌願者進行配對研究。記錄併分析瞭患者靜脈血測定血清鈣、燐、堿性燐痠酶，併進行骨密度測定。結果兩組鈣、燐及堿性燐痠酶水平無明顯差異，銀屑病組血清鈣略低于對照組，但無統計學差異，而血清燐水平平均差異不顯著；2組腰椎及股骨頸骨密度比較，銀屑病組均低于對照組，且有統計學意義；進一步分析髮現銀屑病組股骨頸骨密度下降較明顯，其差異具有統計學意義。股骨頸骨密度值比較，銀屑病組無論是骨量減低還是骨質疏鬆患者比例明顯高于非銀屑病組。結論男性銀屑病患者骨代謝水平明顯下降。
목적：본연구지재통과대남성은설병환자대사적영향인소적분석，탐토골질소송여은설병적관계，위진일보예방급치료제공의거。방법본조61례명학진단적남성은설병환자균래자아원피부과문진，동시근거년령、체중지수、족별선택61례동기재아원체검중심체검적남성지원자진행배대연구。기록병분석료환자정맥혈측정혈청개、린、감성린산매，병진행골밀도측정。결과량조개、린급감성린산매수평무명현차이，은설병조혈청개략저우대조조，단무통계학차이，이혈청린수평평균차이불현저；2조요추급고골경골밀도비교，은설병조균저우대조조，차유통계학의의；진일보분석발현은설병조고골경골밀도하강교명현，기차이구유통계학의의。고골경골밀도치비교，은설병조무론시골량감저환시골질소송환자비례명현고우비은설병조。결론남성은설병환자골대사수평명현하강。
Objective By analyzing the influential factors in male patients with psoriasis, to investigate the relationship between osteoporosis and psoriasis, and to provide theoretical basis for the prevention and treatment.Methods All the 61 male patients with psoriasis in this study were selected from the Out-patient Department of Dermatology in our hospital.Simultaneously, 61 male volunteers, who received health examination in our medical examination center, were selected as matched-pairs according to age, body mass index, and the nationality.The serum calcium, phosphorus, and alkaline phosphatase ( ALP) of all the patients were recorded and analyzed.The bone mineral density of all the patients was also detected.Results The serum calcium, phosphorus, and ALP in two groups showed no significant difference.The serum level of calcium in psoriasis group was slightly lower than that in control group, but with no significant difference.And the serum level of phosphorus also showed no significant difference.BMD of the lumbar vertebrae and the femoral neck in psoriasis group was significantly lower than that in control group.Further analysis revealed that BMD of the femoral neck in psoriasis group decreased significantly.BMD of the femoral neck in psoriasis group, either in patients with bone mass loss or in patients with osteoporosis, was significantly higher than that in control group. Conclusion The bone metabolism level in male patients with psoriasis decreases significantly.
