CAJ | 학술논문

目的：探讨以不明原因发热（FUO）为首发表现的恶性肿瘤患者的病因构成特点和诊断难点。方法回顾性分析2003年1-2013年8月住院且符合 FUO 诊断标准的恶性肿瘤患者31例。男20例，女11例，平均年龄（55．5±16．0）岁。结果31例患者中，淋巴/造血组织肿瘤26例（83．9％，其中淋巴瘤16例），实体瘤5例（16．1％）。发热程度通常为高热，伴随症状以畏寒、寒战、乏力盗汗、体质量减轻为主；患者具有热程、住院时间、确诊时间长等特点，患者最终确诊与初步诊断不符合18例（58．1％）。结论以 FUO 为首发表现的恶性肿瘤患者中，淋巴/造血组织肿瘤是最主要的病因，其中淋巴瘤最为常见。长期发热的恶性肿瘤患者容易误诊，在 FUO 病因诊断中，应警惕恶性肿瘤性疾病的可能。
목적：탐토이불명원인발열（FUO）위수발표현적악성종류환자적병인구성특점화진단난점。방법회고성분석2003년1-2013년8월주원차부합 FUO 진단표준적악성종류환자31례。남20례，녀11례，평균년령（55．5±16．0）세。결과31례환자중，림파/조혈조직종류26례（83．9％，기중림파류16례），실체류5례（16．1％）。발열정도통상위고열，반수증상이외한、한전、핍력도한、체질량감경위주；환자구유열정、주원시간、학진시간장등특점，환자최종학진여초보진단불부합18례（58．1％）。결론이 FUO 위수발표현적악성종류환자중，림파/조혈조직종류시최주요적병인，기중림파류최위상견。장기발열적악성종류환자용역오진，재 FUO 병인진단중，응경척악성종류성질병적가능。
Objective To explore fever of unknown origin (FUO) as the first manifestation of the characteristics of patients with malignant etiology and diagnosis difficult .Methods Retrospectively analyzed 31 patients with FUO who were hospitalized from January 2003 to August 2013.20 males and 11 females, age (55.5 ±16.0) years old.Results Among the 31 patients, the lymphatic /hematopoietic tissue tumors in 26 cases (83.9%), solid tumors of 5 cases (16.1%).These patients usually had high fever , accompanied by symptoms of chills , chills, fatigue, night sweats and weight loss based ; pa-tients'fever, hospitalization, diagnosed with longer time.Patients eventually diagnosed with a preliminary diagnosis does not meet in 18 cases (58.1%).Conclusion Lymphatic /hematopoietic tissue tumor was the most main cause in malignant neo -plasm patients first presenting with FUO, and lymphoma was the main cause of lymphatic /hematopoietic tissue tumor.Malig-nant neoplasm patients of long term fever were easily misdiagnosed ;should be alert to the possibility of tumor diseases in FUO etiology diagnosis.