疑难病杂志
疑難病雜誌
의난병잡지
JOURNAL OF DIFFICULT AND COMPLICATED CASES
2014年
3期
249-252,255
,共5页
牛晓婷%胡红%许菡苡%白雪
牛曉婷%鬍紅%許菡苡%白雪
우효정%호홍%허함이%백설
哮喘%哮喘控制测试%哮喘控制问卷%综合医院焦虑抑郁量表%焦虑%抑郁%相关性
哮喘%哮喘控製測試%哮喘控製問捲%綜閤醫院焦慮抑鬱量錶%焦慮%抑鬱%相關性
효천%효천공제측시%효천공제문권%종합의원초필억욱량표%초필%억욱%상관성
Asthma%Asthma cotrol test%Asthma control questionnaire%General hospital anxiety and depression scale%Anxiety%Depression%Relevance
目的:探讨支气管哮喘(简称哮喘)的控制水平与焦虑抑郁情绪的关系,分析哮喘患者焦虑抑郁发生的可能原因。方法入选2012年5月-2013年5月解放军总医院呼吸科门诊62例哮喘患者进行横断面研究,评估其哮喘控制水平、肺功能及焦虑抑郁情绪。采用2008年支气管哮喘防治指南的控制标准评估哮喘控制水平。采用综合医院焦虑抑郁量表(HAD)评测焦虑和抑郁情绪。将62例患者分为完全控制组、部分控制组及未控制组,分析不同哮喘控制水平与患者焦虑抑郁情绪的关系。结果62例哮喘患者中存在焦虑18例(29.0%),抑郁20例(32.3%),同时存在焦虑和抑郁10例(16.1%)。病程和年龄与抑郁分数之间存在显著正相关( r =0.300, P <0.05; r =0.307, P <0.05),而与焦虑分数之间无显著相关( r =0.222, P >0.05; r =-0.023, P >0.05)。未控制组患者焦虑和抑郁分数和发生率均明显高于完全控制组及部分控制组( P <0.01, P <0.05)。哮喘控制良好与焦虑和抑郁情绪发生率呈负相关( r 值分别为-0.334和-0.416, P <0.01)。 ACT 评分与焦虑和抑郁分数之间存在显著负相关( r =-0.341, P <0.01; r =-0.464, P <0.01)。 ACQ 评分与焦虑和抑郁分数之间存在显著正相关( r =0.378, P <0.01; r =0.443, P <0.01)。 FEV1%与焦虑抑郁分数之间无显著相关( r =-0.096, P >0.05; r =-0.126, P >0.05)。PEF%与焦虑抑郁分数之间无显著相关( r =-0.240, P >0.05; r =-0.240, P >0.05)。焦虑组与非焦虑组相比,FEV1%、PEF%较低,但差异无统计学意义( P >0.05)。抑郁组与非抑郁组相比,FEV1%、PEF%较低,但差异无统计学意义( P >0.05)。气道炎性指标(FeNO)与焦虑抑郁分数之间无显著相关( r =0.014, P >0.05; r =-0.073, P >0.05)。结论近1/3的哮喘患者伴有焦虑抑郁情绪。哮喘控制水平与患者焦虑抑郁情绪密切相关,哮喘控制不佳可增加患者焦虑和抑郁的发生率。哮喘症状未控制、生活质量下降可能是哮喘患者发生焦虑抑郁情绪的重要原因。焦虑抑郁情况与患者肺功能和气道炎性指标之间无显著相关性。
目的:探討支氣管哮喘(簡稱哮喘)的控製水平與焦慮抑鬱情緒的關繫,分析哮喘患者焦慮抑鬱髮生的可能原因。方法入選2012年5月-2013年5月解放軍總醫院呼吸科門診62例哮喘患者進行橫斷麵研究,評估其哮喘控製水平、肺功能及焦慮抑鬱情緒。採用2008年支氣管哮喘防治指南的控製標準評估哮喘控製水平。採用綜閤醫院焦慮抑鬱量錶(HAD)評測焦慮和抑鬱情緒。將62例患者分為完全控製組、部分控製組及未控製組,分析不同哮喘控製水平與患者焦慮抑鬱情緒的關繫。結果62例哮喘患者中存在焦慮18例(29.0%),抑鬱20例(32.3%),同時存在焦慮和抑鬱10例(16.1%)。病程和年齡與抑鬱分數之間存在顯著正相關( r =0.300, P <0.05; r =0.307, P <0.05),而與焦慮分數之間無顯著相關( r =0.222, P >0.05; r =-0.023, P >0.05)。未控製組患者焦慮和抑鬱分數和髮生率均明顯高于完全控製組及部分控製組( P <0.01, P <0.05)。哮喘控製良好與焦慮和抑鬱情緒髮生率呈負相關( r 值分彆為-0.334和-0.416, P <0.01)。 ACT 評分與焦慮和抑鬱分數之間存在顯著負相關( r =-0.341, P <0.01; r =-0.464, P <0.01)。 ACQ 評分與焦慮和抑鬱分數之間存在顯著正相關( r =0.378, P <0.01; r =0.443, P <0.01)。 FEV1%與焦慮抑鬱分數之間無顯著相關( r =-0.096, P >0.05; r =-0.126, P >0.05)。PEF%與焦慮抑鬱分數之間無顯著相關( r =-0.240, P >0.05; r =-0.240, P >0.05)。焦慮組與非焦慮組相比,FEV1%、PEF%較低,但差異無統計學意義( P >0.05)。抑鬱組與非抑鬱組相比,FEV1%、PEF%較低,但差異無統計學意義( P >0.05)。氣道炎性指標(FeNO)與焦慮抑鬱分數之間無顯著相關( r =0.014, P >0.05; r =-0.073, P >0.05)。結論近1/3的哮喘患者伴有焦慮抑鬱情緒。哮喘控製水平與患者焦慮抑鬱情緒密切相關,哮喘控製不佳可增加患者焦慮和抑鬱的髮生率。哮喘癥狀未控製、生活質量下降可能是哮喘患者髮生焦慮抑鬱情緒的重要原因。焦慮抑鬱情況與患者肺功能和氣道炎性指標之間無顯著相關性。
목적:탐토지기관효천(간칭효천)적공제수평여초필억욱정서적관계,분석효천환자초필억욱발생적가능원인。방법입선2012년5월-2013년5월해방군총의원호흡과문진62례효천환자진행횡단면연구,평고기효천공제수평、폐공능급초필억욱정서。채용2008년지기관효천방치지남적공제표준평고효천공제수평。채용종합의원초필억욱량표(HAD)평측초필화억욱정서。장62례환자분위완전공제조、부분공제조급미공제조,분석불동효천공제수평여환자초필억욱정서적관계。결과62례효천환자중존재초필18례(29.0%),억욱20례(32.3%),동시존재초필화억욱10례(16.1%)。병정화년령여억욱분수지간존재현저정상관( r =0.300, P <0.05; r =0.307, P <0.05),이여초필분수지간무현저상관( r =0.222, P >0.05; r =-0.023, P >0.05)。미공제조환자초필화억욱분수화발생솔균명현고우완전공제조급부분공제조( P <0.01, P <0.05)。효천공제량호여초필화억욱정서발생솔정부상관( r 치분별위-0.334화-0.416, P <0.01)。 ACT 평분여초필화억욱분수지간존재현저부상관( r =-0.341, P <0.01; r =-0.464, P <0.01)。 ACQ 평분여초필화억욱분수지간존재현저정상관( r =0.378, P <0.01; r =0.443, P <0.01)。 FEV1%여초필억욱분수지간무현저상관( r =-0.096, P >0.05; r =-0.126, P >0.05)。PEF%여초필억욱분수지간무현저상관( r =-0.240, P >0.05; r =-0.240, P >0.05)。초필조여비초필조상비,FEV1%、PEF%교저,단차이무통계학의의( P >0.05)。억욱조여비억욱조상비,FEV1%、PEF%교저,단차이무통계학의의( P >0.05)。기도염성지표(FeNO)여초필억욱분수지간무현저상관( r =0.014, P >0.05; r =-0.073, P >0.05)。결론근1/3적효천환자반유초필억욱정서。효천공제수평여환자초필억욱정서밀절상관,효천공제불가가증가환자초필화억욱적발생솔。효천증상미공제、생활질량하강가능시효천환자발생초필억욱정서적중요원인。초필억욱정황여환자폐공능화기도염성지표지간무현저상관성。
Objective To analysis bronchial asthma (asthma) control level and its relationship with anxiety or de -pression, to explore the possible reason of anxiety and depression of asthma patients .Methods Selected from May 2012 to May 2013, 62 cases of clinic patients in PLA General Hospital , conducted a cross-sectional study of pulmonary with asthma , to assess their level of asthma control , lung function and anxiety and depression .By using 2008 Standard Guide Bronchial Asthma control criterion to assess asthma control level .Integrated hospital anxiety and depression scale (HAD) to evaluate of anxiety and depression.62 patients were divided into an entirely control group , partially control group and the non-control group to analyze the relationship between different levels of asthma control in patients with anxiety and depression .Results Anxiety in 18 cases (29.0%), depression in 20 patients (32.3%) in the presence of 62 cases of patients with asthma, and the presence of anxiety and depression in 10 patients (16.1%).Between duration and age and depression scores were signifi -cantly positively correlated ( r =0.300, P <0.05; r =0.307, P <0.05), while between anxiety scores and no significant correlation ( r =0.222, P >0.05; r =-0.023, P >0.05).No control group of patients and incidence of anxiety and de -pression scores were significantly higher than the control group and some completely control group ( P <0.01, P <0.05). Asthma is well controlled and the incidence of anxiety and depression were negatively correlated (r values were -0.334 and-0.416, P <0.01).Between ACT scores and anxiety and depression scores were significantly negatively correlated ( r =-0.341, P <0.01; r =-0.464, P <0.01).ACQ score between anxiety and depression scores were significantly positively correlated ( r =0.378, P <0.01; r =0.443, P <0.01).FEV no significant correlation between 1% and anxiety and de-pression scores ( r =-0.096, P >0.05; r =-0.126, P >0.05).There was no significant correlation between PEF %with anxiety and depression scores ( r =-0.240, P >0.05; r =-0.240, P >0.05).Anxiety group compared with the non-anxious group, FEV1%, PEF% lower, but the difference was not statistically significant ( P >0.05).Depression group compared with non-depressed group, FEV1%, PEF% lower, but the difference was not statistically significant ( P >0.05). There was no significant correlation between airway inflammatory markers (FeNO) and anxiety and depression scores ( r =0.014, P >0.05; r =-0.073, P >0.05).Conclusion Nearly a third of the asthmatic patients suffer from anxiety and de -pression.Level of asthma control in patients with anxiety and depression are closely related to poorly controlled asthma may in -crease the incidence of anxiety and depression .Uncontrolled asthma symptoms, quality of life may be an important cause of asthma patients with anxiety and depression .There was no significant correlation between anxiety and depression in patients with lung function and airway conditions and inflammatory markers .