CAJ | 학술논문

目的：观察外用青黛膏治疗外阴白色病变的临床疗效。方法27例经外阴活检证实的外阴白色病变患者，鳞状细胞增生型12例，硬化性苔藓型8例，硬化性苔藓型伴鳞状细胞增生型（混合型）4例，不典型增生型3例，经青黛膏治疗1个疗程后，观察其外阴皮肤黏膜色素变化及临床症状改善情况。结果27例外阴白色病变患者经青黛膏治疗后的有效率为100％，治疗后鳞状细胞增生型、硬化苔藓型、混合型及不典型增生型病变外阴局部皮肤弹性评分与本证型治疗前比较差异均有统计学意义（P 均＜0．05）。结论外用青黛膏治疗外阴白色病变是一种无创、无毒副作用、经济、安全的治疗方法，值得临床推广应用。
목적：관찰외용청대고치료외음백색병변적림상료효。방법27례경외음활검증실적외음백색병변환자，린상세포증생형12례，경화성태선형8례，경화성태선형반린상세포증생형（혼합형）4례，불전형증생형3례，경청대고치료1개료정후，관찰기외음피부점막색소변화급림상증상개선정황。결과27예외음백색병변환자경청대고치료후적유효솔위100％，치료후린상세포증생형、경화태선형、혼합형급불전형증생형병변외음국부피부탄성평분여본증형치료전비교차이균유통계학의의（P 균＜0．05）。결론외용청대고치료외음백색병변시일충무창、무독부작용、경제、안전적치료방법，치득림상추엄응용。
Objective To observe the clinical therapeutic effects of Qingdai Ointment in the treatment of white lesions of vulva.Methods To observe the vulvar mucocutaneous pigmentation changes and clinical symptoms improvments of 27 cases confirmed by vulval biopsy after treatment with indigo naturalis oint-ment.Results Compared with before treatment with indigo Naturalis ointment,vulva local skin elasticity differences were statistically significant (P <0.05).Conclusion Topical indigo naturalis ointment in the treatment of vulvar white lesion is a noninvasive treatment,with the merits of few side effect,low cost, safety.It is highly recommended in clinical application.