临床儿科杂志
臨床兒科雜誌
림상인과잡지
2014年
3期
218-219
,共2页
组织细胞增生症%朗格罕斯细胞%诊断
組織細胞增生癥%朗格罕斯細胞%診斷
조직세포증생증%랑격한사세포%진단
histiocytosis%Langerhans cell%diagnosis
目的：了解新生儿朗格罕斯细胞组织细胞增生症（LCH）的临床、实验室特点及诊断要点。方法回顾性分析1例新生儿LCH的临床资料。结果女性患儿，生后1 d因少吃、少哭，皮疹入院，头部、四肢、躯干、脚趾、口腔可见多发皮疹，突出皮面，大小不等，部分破溃结痂。皮肤活检提示病变组织表达S-100（+），CD1α（+），符合LCH诊断。结论新生儿生后有特殊皮疹，需警惕LCH，应进行皮肤活检，以免误诊。
目的：瞭解新生兒朗格罕斯細胞組織細胞增生癥（LCH）的臨床、實驗室特點及診斷要點。方法迴顧性分析1例新生兒LCH的臨床資料。結果女性患兒，生後1 d因少喫、少哭，皮疹入院，頭部、四肢、軀榦、腳趾、口腔可見多髮皮疹，突齣皮麵，大小不等，部分破潰結痂。皮膚活檢提示病變組織錶達S-100（+），CD1α（+），符閤LCH診斷。結論新生兒生後有特殊皮疹，需警惕LCH，應進行皮膚活檢，以免誤診。
목적：료해신생인랑격한사세포조직세포증생증（LCH）적림상、실험실특점급진단요점。방법회고성분석1례신생인LCH적림상자료。결과녀성환인，생후1 d인소흘、소곡，피진입원，두부、사지、구간、각지、구강가견다발피진，돌출피면，대소불등，부분파궤결가。피부활검제시병변조직표체S-100（+），CD1α（+），부합LCH진단。결론신생인생후유특수피진，수경척LCH，응진행피부활검，이면오진。
Objective To understand the clinical features and laboratory examination and diagnosis of Langerhas cell histio-cytosis (LCH) in newborns. Methods Retrospective analysis of the clinical data of a neonatal case of LCH was performed. Results A one-day-old girl was admitted with chief complaint of eating less, less crying and skin rash for one day. The unequal sized rash was on the head, limbs, trunk, toe and oral mucosa. The skin rashes were protruding from the skin and were partially broken and crusted. Biopsy of the skin tissue showed the expression of S-100 and CD1α, consistent with the diagnosis of LCH. Conclusions When new-borns have special rash after birth, LCH should be considered. To avoid misdiagnosis, skin biopsy should be performed.
