实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2014年
3期
346-348
,共3页
骨肉瘤%病理骨折%预后因素%临床特点
骨肉瘤%病理骨摺%預後因素%臨床特點
골육류%병리골절%예후인소%림상특점
Osteosarcoma%Pathological fracture%Prognostic factors%Clinical characteristics
目的：探讨肢体骨肉瘤并发病理性骨折的临床特点及相关影响因素。方法选择154例肢体骨肉瘤患者，给予相关治疗，分析骨肉瘤患者预后情况及合并病理性骨折的相关因素。结果骨肉瘤合并病理骨折发生率为20．1％。将单因素分析中有统计学意义的肿瘤位置、肿瘤大小及局部复发等3项进行多因素分析，肿瘤大小（ P＝0．001）、局部复发（P＝0．001）为肢体骨肉瘤合并病理性骨折的独立预后影响因素。结论肿瘤体积较大、有局部复发的骨肉瘤患者较容易合并病理性骨折，且预后相对较差。
目的：探討肢體骨肉瘤併髮病理性骨摺的臨床特點及相關影響因素。方法選擇154例肢體骨肉瘤患者，給予相關治療，分析骨肉瘤患者預後情況及閤併病理性骨摺的相關因素。結果骨肉瘤閤併病理骨摺髮生率為20．1％。將單因素分析中有統計學意義的腫瘤位置、腫瘤大小及跼部複髮等3項進行多因素分析，腫瘤大小（ P＝0．001）、跼部複髮（P＝0．001）為肢體骨肉瘤閤併病理性骨摺的獨立預後影響因素。結論腫瘤體積較大、有跼部複髮的骨肉瘤患者較容易閤併病理性骨摺，且預後相對較差。
목적：탐토지체골육류병발병이성골절적림상특점급상관영향인소。방법선택154례지체골육류환자，급여상관치료，분석골육류환자예후정황급합병병이성골절적상관인소。결과골육류합병병리골절발생솔위20．1％。장단인소분석중유통계학의의적종류위치、종류대소급국부복발등3항진행다인소분석，종류대소（ P＝0．001）、국부복발（P＝0．001）위지체골육류합병병이성골절적독립예후영향인소。결론종류체적교대、유국부복발적골육류환자교용역합병병이성골절，차예후상대교차。
Objective To investigate the clinical characteristics and related factors of limb osteosarcoma with pathologi -cal fracture .Methods 154 osteosarcoma patients were selected and received related treatment ,prognosis and related factors of intercurrent pathological fracture were analyzed .Results Incidence rate of osteosarcoma with pathological fracture was 20.1%. Single factor analysis showed that tumor location ,tumor size and local recurrence had statistical difference ,and these 3 items were analyzed by multiple-factor analysis analysis.Tumor size (P=0.001) and local recurrence (P=0.001) were independent prog-nostic factors affecting limb osteosarcoma with pathological fracture .Conclusion Limb osteosarcoma with larger tumor size and local recurrence is more likely intercurrent pathological fracture ,and with relatively poor prognosis .
