CAJ | 학술논문

目的：探讨子宫内膜间质肉瘤的临床病理学特点。方法回顾性分析43例子宫内膜间质肉瘤的临床病理资料。结果低度恶性子宫内膜间质肉瘤平均发病年龄为44．2岁，未分化子宫内膜间质肉瘤为52．6岁。临床表现为不规则阴道出血、子宫增大。 B超检查显示子宫中、低回声团块。病理大体：肿瘤为单个或多个黄色、褐色的质软肿物，可呈息肉样突向宫腔，常伴有肌层结节状肿物，边界清。镜下：肿瘤细胞与增殖期子宫内膜细胞相似，呈短梭形，胞质少，围绕螺旋小动脉样血管分布。结论 ESS临床表现缺乏特异性，术前诊断性刮宫非常重要，必要时术中行快速冰冻检查，CD10可作为诊断子宫内膜间质肉瘤的特异性标志物。
목적：탐토자궁내막간질육류적림상병이학특점。방법회고성분석43례자궁내막간질육류적림상병리자료。결과저도악성자궁내막간질육류평균발병년령위44．2세，미분화자궁내막간질육류위52．6세。림상표현위불규칙음도출혈、자궁증대。 B초검사현시자궁중、저회성단괴。병리대체：종류위단개혹다개황색、갈색적질연종물，가정식육양돌향궁강，상반유기층결절상종물，변계청。경하：종류세포여증식기자궁내막세포상사，정단사형，포질소，위요라선소동맥양혈관분포。결론 ESS림상표현결핍특이성，술전진단성괄궁비상중요，필요시술중행쾌속빙동검사，CD10가작위진단자궁내막간질육류적특이성표지물。
Objective To investigate the clinicopathologic features of endometrial stromal sarcoma (ESS).Methods Retrospectivly study the clinical and pathological data of 43 cases of endometrial stromal sarcoma .Results The average age of LGESS was 44.2 years and that of UESS was 52.6 years.Most clinical manifestations were irregular vaginal bleeding and enlarge-ment of uterus .B ultrasound examination showed that middle ,low level echo was located in uterus .ESS grossly appeared as sharp-ly defined,solitary or multiple,yellowish or brown and soft tumors with the polypoid nodules located in the muscular layer towards the cavity of uterus.Microscopically,tumor cells were similar to the proliferative endometrial .They showed short spindle-shaped and slight cytoplasm and were distributed around spiral arteriola type vessels .Conclusion Clinical manifestations of ESS are not special.Preoperative diagnostic curettage is significant .If necessary,intraoperative frozen check is performed .CD10 can serve as the special marker in the diagnosis of ESS .