国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
5期
555-556
,共2页
哮喘%免疫球蛋白E%变应原%螨
哮喘%免疫毬蛋白E%變應原%螨
효천%면역구단백E%변응원%만
asthma%immunoglobulin E%allergens%mites
目的：探讨血清尘螨特异性免疫球蛋白E （Ig E ）检测在小儿哮喘诊断与防治的应用。方法该院在2008年2月至2010年4月收治52例小儿哮喘患儿为观察组，＜3岁患儿有11例，3～＜7岁患儿有18例，7～＜12岁患儿有23例；健康儿童44例为对照组，＜3岁患儿有8例，3～＜7岁患儿有16例，7～＜12岁患儿有20例。两组研究对象都进行血清尘螨特异性Ig E检测。结果观察组的血清尘螨特异性IgE浓度为（152．78±48．95）U/mL ；对照组的血清尘螨特异性IgE浓度为（25．62±6．49） U/mL ，观察组患儿的血清尘螨特异性IgE浓度明显高于对照组，差异有统计学意义（P＜0．05）。结论小儿哮喘患儿的血清尘螨特异性Ig E阳性率很高，尤其7～＜12岁患儿阳性率最高，所以尘螨过敏原是诱发小儿哮喘的重要因素，通过血清尘螨特异性Ig E检查有助于发现尘螨过敏原，对防治由尘螨过敏原诱发小儿哮喘的重要手段，值得临床推广应用。
目的：探討血清塵螨特異性免疫毬蛋白E （Ig E ）檢測在小兒哮喘診斷與防治的應用。方法該院在2008年2月至2010年4月收治52例小兒哮喘患兒為觀察組，＜3歲患兒有11例，3～＜7歲患兒有18例，7～＜12歲患兒有23例；健康兒童44例為對照組，＜3歲患兒有8例，3～＜7歲患兒有16例，7～＜12歲患兒有20例。兩組研究對象都進行血清塵螨特異性Ig E檢測。結果觀察組的血清塵螨特異性IgE濃度為（152．78±48．95）U/mL ；對照組的血清塵螨特異性IgE濃度為（25．62±6．49） U/mL ，觀察組患兒的血清塵螨特異性IgE濃度明顯高于對照組，差異有統計學意義（P＜0．05）。結論小兒哮喘患兒的血清塵螨特異性Ig E暘性率很高，尤其7～＜12歲患兒暘性率最高，所以塵螨過敏原是誘髮小兒哮喘的重要因素，通過血清塵螨特異性Ig E檢查有助于髮現塵螨過敏原，對防治由塵螨過敏原誘髮小兒哮喘的重要手段，值得臨床推廣應用。
목적：탐토혈청진만특이성면역구단백E （Ig E ）검측재소인효천진단여방치적응용。방법해원재2008년2월지2010년4월수치52례소인효천환인위관찰조，＜3세환인유11례，3～＜7세환인유18례，7～＜12세환인유23례；건강인동44례위대조조，＜3세환인유8례，3～＜7세환인유16례，7～＜12세환인유20례。량조연구대상도진행혈청진만특이성Ig E검측。결과관찰조적혈청진만특이성IgE농도위（152．78±48．95）U/mL ；대조조적혈청진만특이성IgE농도위（25．62±6．49） U/mL ，관찰조환인적혈청진만특이성IgE농도명현고우대조조，차이유통계학의의（P＜0．05）。결론소인효천환인적혈청진만특이성Ig E양성솔흔고，우기7～＜12세환인양성솔최고，소이진만과민원시유발소인효천적중요인소，통과혈청진만특이성Ig E검사유조우발현진만과민원，대방치유진만과민원유발소인효천적중요수단，치득림상추엄응용。
Objective To explore the application of serum dust mite specific IgE detection in the diagnosis and treatment of child asthma .Methods 52 children cases of asthma in this hospital from February 2008 to April 2010 were selected as the observation group ,11 cases were <3 years old ,18 cases were 3- < 7 years old and 23 cases were 7- <12 years old ;44 healthy children were taken as the control group ,8 cases were <3 years old ,16 cases were 3- < 7 years old and 20 cases were 7- <12 years old .The two groups were detected the serum dust mite specific Ig E .Results The serum dust mite specific Ig E was (152 .78 ± 48 .95) U/mL in the observation group and (25 .62 ± 6 .49) U/mL in the control group ,the serum dust mite specific Ig E concentration in the observation group was significantly higher than that in the control group ,the difference showed the statistical significance (P<0 .05) .Conclusion The positive rate of serum dust mite specific IgE in child asthma is very high ,especially the children patients of 7- <12 years old have the highest positive rate .Therefore ,the dust mite allergen is the important factor inducing child asthma .The detection of serum dust mite specific IgE is conducive to find the dust mite allergen ,which is an important measure for preventing and treating child asthma induced by the dust mite allergen and is worthy of being promoted in clinic .
