CAJ | 학술논문

目的：探讨高湿高海拔环境下，中青年人群血清胸苷激酶1（TK1）水平差异。方法利用增强化学发光法对世居高湿高海拔地区128例中青年体检人群血清TK1进行检测。结果对照组 TK1水平为（1．7842±0．1279）pmol/L ，实验组 TK1水平为（1．3850±0．0785）pmol/L ，两组 TK1水平比较差异有统计学意义（P＜0．01）；对照组 TK1阳性者28例，阳性率为30．43％，实验组TK1阳性者为2例，阳性率为5．56％，两组阳性率比较差异有统计学意义（P＜0．01）；对照组女性TK1水平高于男性，差异有统计学意义（P＜0．05）。结论检测高湿高海拔地区人群血清 TK1水平对于特殊环境不同年龄段人群体检、肿瘤预防具有积极的指导意义。
목적：탐토고습고해발배경하，중청년인군혈청흉감격매1（TK1）수평차이。방법이용증강화학발광법대세거고습고해발지구128례중청년체검인군혈청TK1진행검측。결과대조조 TK1수평위（1．7842±0．1279）pmol/L ，실험조 TK1수평위（1．3850±0．0785）pmol/L ，량조 TK1수평비교차이유통계학의의（P＜0．01）；대조조 TK1양성자28례，양성솔위30．43％，실험조TK1양성자위2례，양성솔위5．56％，량조양성솔비교차이유통계학의의（P＜0．01）；대조조녀성TK1수평고우남성，차이유통계학의의（P＜0．05）。결론검측고습고해발지구인군혈청 TK1수평대우특수배경불동년령단인군체검、종류예방구유적겁적지도의의。
Objective To investigate the difference of serum thymidine kinase 1(TK1) levels of young and middle-aged people in high humidity and high altitude area .Methods Serum level of TK1 was measured with the enhanced chemiluminescence method in 128 native young and middle-aged people .Results Serum TK1 was (1 .784 2 ± 0 .127 9)pmol/L in the control group and (1 .385 0 ± 0 .078 5)pmol/L in the test group ,the difference between them had statistical significance (P<0 .01) .28 cases in the control group were TK1 positive with the positive rate of 30 .43% ,while 2 cases in the test group were TK1 positive with the posi-tive rate of 5 .56% ,the positive rates had statistical difference between the two groups (P<0 .01) .In the control group ,the TK1 level in females was higher than that in males ,the difference between them showed statistical significance (P<0 .05) .Conclusion Detecting serum TK1 in the population of high humidity and high altitude areas has the active significance for guiding the physical examination and cancer prevention of different age groups under the special environment .