CAJ | 학술논문

目的：结合酶联免疫吸附试验(ELISA)和梅毒螺旋体凝集试验(TPPA)检测，分析并进一步讨论老年人梅毒阳性率与临床意义。方法：选择经ELISA法检测的12103例门诊及住院患者，分为非老年组(<60岁，9145例)和老年组(≥60岁，2158例)，其中阳性标本进一步作TPPA检测，分别对两种方法的两种人群的阳性率进行统计学分析，并对两组人群的阳性符合率进行统计学分析。结果：两种方法检测的阳性率比较，差异有统计学意义(字2=22.04，P<0.05)；两种方法检测的两组人群阳性检出率比较，年龄组差异均有统计学意义(ELISA法：字12=28.64，P1<0.05；TPPA法：字22=18.83，P2<0.05)；其中TPPA法确诊阳性分别为71例和116例，阳性符合率分别为83.53%和91.34%，两者比较差异有统计学意义(P<0.05)。结论：ELISA法与TPPA法的阳性检出率不同，老年人群ELISA和TPPA阳性率比非老年人群高，老年人的阳性符合率比非老年人群高。故临床诊断需结合其他方法综合判断，以减少误差，提高梅毒检出率和正确率。
목적：결합매련면역흡부시험(ELISA)화매독라선체응집시험(TPPA)검측，분석병진일보토론노년인매독양성솔여림상의의。방법：선택경ELISA법검측적12103례문진급주원환자，분위비노년조(<60세，9145례)화노년조(≥60세，2158례)，기중양성표본진일보작TPPA검측，분별대량충방법적량충인군적양성솔진행통계학분석，병대량조인군적양성부합솔진행통계학분석。결과：량충방법검측적양성솔비교，차이유통계학의의(자2=22.04，P<0.05)；량충방법검측적량조인군양성검출솔비교，년령조차이균유통계학의의(ELISA법：자12=28.64，P1<0.05；TPPA법：자22=18.83，P2<0.05)；기중TPPA법학진양성분별위71례화116례，양성부합솔분별위83.53%화91.34%，량자비교차이유통계학의의(P<0.05)。결론：ELISA법여TPPA법적양성검출솔불동，노년인군ELISA화TPPA양성솔비비노년인군고，노년인적양성부합솔비비노년인군고。고림상진단수결합기타방법종합판단，이감소오차，제고매독검출솔화정학솔。
Objective:To analyze and further discuss the positive rate of syphilis in old patients by method of Enzyme-linked immunosorbent assay (ELISA) and treponema pallidum particle assay(TPPA) test. Method:A total of 12 103 outpatient and hospitalized patients tested by ELISA were selected,and they were divided into the control group(<60 years,n=9145) and the elderly group(≥60 years,n=2158),and the positive specimens applied TPPA test further.The differences of the positive rate and the positive coincident rate of the two groups in the two methods were respectively analyzed. Result:The positive rates of the two methods were compared,and the difference was statistically significant(X2=22.04,P<0.05).The positive rates of two age groups in the two methods were compared, and the differences were statistically significant(TP-ELISA:X12=28.64,P1<0.05;TPPA:X22=18.83,P2<0.05).The positive cases confirmed by TPPA were 71 cases and 116 cases,and the positive coincident rate were 83.53%and 91.34%respectively. The positive coincident rates of the two age groups were compared,and the difference was statistically significant.Conclusion:The detectable rates of the two methods are different.The positive rate of the elder is higher than that of the young.The positive coincident rate of the elder was higher than that of young.Therefore,the clinical diagnosis should combine other methods to reduce the error and promote the detection rate and accuracy of treponema pallidum.