中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
8期
1-2,3
,共3页
结直肠肿瘤%肠道抗菌准备%菌群失调
結直腸腫瘤%腸道抗菌準備%菌群失調
결직장종류%장도항균준비%균군실조
Colorectal neoplasms%Intestinal antibiotic preparation%Dysbacteriosis
目的：探讨大肠癌术前口服肠道抗菌素行肠道准备的必要性。方法：选取2011年6月-2012年6月中国医科大学附属第一医院肿瘤外科收治的100例大肠癌患者，采用随机数字表法将其分为试验组和对照组，各50例。试验组术前未口服抗生素行肠道准备，其他治疗同传统方式。对照组术前行传统肠道准备。观察两组患者手术前、后粪便细菌球杆比例及术后并发症。结果：两组患者术前粪便细菌球杆比例均正常，术后大便细菌涂片检查肠道细菌球杆比例均有不同程度变化。试验组患者术后肠道细菌球杆比例失调者5例，程度相对较轻；腹泻2例。对照组术后肠道细菌球杆比例失调者13例，程度相对较重，腹泻8例。试验组术后肠道细菌球杆失调比例明显低于对照组，差异有统计学意义(P<0.05)。但两组患者术后平均住院时间、感染性相关并发症方面比较差异无统计学意义(P>0.05)。结论：大肠癌术前肠道准备不需使用肠道抗菌药物。
目的：探討大腸癌術前口服腸道抗菌素行腸道準備的必要性。方法：選取2011年6月-2012年6月中國醫科大學附屬第一醫院腫瘤外科收治的100例大腸癌患者，採用隨機數字錶法將其分為試驗組和對照組，各50例。試驗組術前未口服抗生素行腸道準備，其他治療同傳統方式。對照組術前行傳統腸道準備。觀察兩組患者手術前、後糞便細菌毬桿比例及術後併髮癥。結果：兩組患者術前糞便細菌毬桿比例均正常，術後大便細菌塗片檢查腸道細菌毬桿比例均有不同程度變化。試驗組患者術後腸道細菌毬桿比例失調者5例，程度相對較輕；腹瀉2例。對照組術後腸道細菌毬桿比例失調者13例，程度相對較重，腹瀉8例。試驗組術後腸道細菌毬桿失調比例明顯低于對照組，差異有統計學意義(P<0.05)。但兩組患者術後平均住院時間、感染性相關併髮癥方麵比較差異無統計學意義(P>0.05)。結論：大腸癌術前腸道準備不需使用腸道抗菌藥物。
목적：탐토대장암술전구복장도항균소행장도준비적필요성。방법：선취2011년6월-2012년6월중국의과대학부속제일의원종류외과수치적100례대장암환자，채용수궤수자표법장기분위시험조화대조조，각50례。시험조술전미구복항생소행장도준비，기타치료동전통방식。대조조술전행전통장도준비。관찰량조환자수술전、후분편세균구간비례급술후병발증。결과：량조환자술전분편세균구간비례균정상，술후대편세균도편검사장도세균구간비례균유불동정도변화。시험조환자술후장도세균구간비례실조자5례，정도상대교경；복사2례。대조조술후장도세균구간비례실조자13례，정도상대교중，복사8례。시험조술후장도세균구간실조비례명현저우대조조，차이유통계학의의(P<0.05)。단량조환자술후평균주원시간、감염성상관병발증방면비교차이무통계학의의(P>0.05)。결론：대장암술전장도준비불수사용장도항균약물。
Objective:To assess the necessity of preoperative intestinal preparation using oral antibiotic in colorectal cancer. Method:Selection from June 2011 to June 2012,the first hospital affiliated to China medical university at the records of 100 patients with colorectal cancer surgical oncology,using the random number table method divided into trial group and control group,50 cases each. Patients preoperative oral antibiotics do bowel preparation,other treatment with traditional way. Control lines of traditional intestinal preparation. After observing two groups of patients before surgery,fecal bacteria cue proportion and postoperative complications.Result:The preoperative intestinal flora,coccus and bacillus ratio were normal in both groups. There were some variation after surgery. 5 cases occurred disorder of coccus and bacillus ratio in test group,and 2 cases occurred diarrhea. However,13 cases occurred disorder of coccus and bacillus ratio in test group,and 8 cases occurred diarrhea. The difference was significant (P<0.05). There was no difference in inpatient time and infectious complications between two groups(P>0.05).Conclusion:Preoperative intestinal preparation need not use oral antibiotic in colorectal cancer.
