CAJ | 학술논문

目的：探讨初发甲状腺功能减退症对患者血清心肌酶、心电图、心脏彩超的影响。方法：选择初发甲状腺功能减退症患者83例，甲状腺功能正常对照者83例，测定入选研究对象的血清心肌酶，并对甲状腺功能减退症组患者进行心脏彩超及心电图检查。结果：初发甲状腺功能减退症组血清肌酸磷酸激酶（CK）、肌酸磷酸激酶同工酶（CK-MB）、乳酸脱氢酶（LDH）、天冬氨酸转氨酶（AST）均较正常对照组升高（P<0.05），以CK-MB升高为明显（P<0.01）。酶学异常患者心电图提示不同程度的心肌缺血，心脏彩超提示不同程度心包积液。经补充甲状腺素治疗后12周，心肌酶及心电图、心脏彩超均基本恢复正常。结论：血清心肌酶水平变化可作为初发甲状腺功能减退症患者病情程度及治疗效果判定的参考。
목적：탐토초발갑상선공능감퇴증대환자혈청심기매、심전도、심장채초적영향。방법：선택초발갑상선공능감퇴증환자83례，갑상선공능정상대조자83례，측정입선연구대상적혈청심기매，병대갑상선공능감퇴증조환자진행심장채초급심전도검사。결과：초발갑상선공능감퇴증조혈청기산린산격매（CK）、기산린산격매동공매（CK-MB）、유산탈경매（LDH）、천동안산전안매（AST）균교정상대조조승고（P<0.05），이CK-MB승고위명현（P<0.01）。매학이상환자심전도제시불동정도적심기결혈，심장채초제시불동정도심포적액。경보충갑상선소치료후12주，심기매급심전도、심장채초균기본회복정상。결론：혈청심기매수평변화가작위초발갑상선공능감퇴증환자병정정도급치료효과판정적삼고。
Objective:To investigate the effect of newly diagnosed hypothyroidism on myocardial enzymes, electrocardiogram,and ultrasonic cardiogram. Method:83 cases of newly diagnosed hypothyroidism and 83 cases of normal control were selected. The levels of enzymes were measured in all cases. The electrocardiogram and ultrasonic cardiogram were carried out in the hypothyroidism group carries. Result:The levels of CK,CK-MB,LDH and AST in the newly diagnosed hypothyroidism group were significantly higher than those in the normal control group(P<0.05),especially the levels of CK-MB(P<0.01). After the treatment,the electrocardiogram,ultrasonic cardiogram and enzymes basically returned to normal. Conclusion:The changes of enzymes in patients with newly diagnosed hypothyroidism may play a benchmark about the severity and treatment.