医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
8期
99-99
,共1页
异甘草酸镁%硫普罗宁%药物性肝损伤
異甘草痠鎂%硫普囉寧%藥物性肝損傷
이감초산미%류보라저%약물성간손상
Magnesium Isoglycyrrhizinate%Tiopronin hepatic dysfunction%Liver Injury induced by chemotherapeutic drugs
目的：比较异甘草酸镁与硫普罗宁治疗恶性肿瘤化疔后药物性肝损伤的疗效与不良反应。方法将86例患者随机分为两组，治疗组予异甘草酸镁注射液150mg，对照组组给予硫普罗宁200mg。结果两组患者治疗后临床症状、体征及肝功能指标较治疗前均有明显改善。结论异甘草酸镁治疗化疗药物性肝损害具有肝功能恢复快、不良反应少的优点，临床疗效优于硫普罗宁。
目的：比較異甘草痠鎂與硫普囉寧治療噁性腫瘤化疔後藥物性肝損傷的療效與不良反應。方法將86例患者隨機分為兩組，治療組予異甘草痠鎂註射液150mg，對照組組給予硫普囉寧200mg。結果兩組患者治療後臨床癥狀、體徵及肝功能指標較治療前均有明顯改善。結論異甘草痠鎂治療化療藥物性肝損害具有肝功能恢複快、不良反應少的優點，臨床療效優于硫普囉寧。
목적：비교이감초산미여류보라저치료악성종류화정후약물성간손상적료효여불량반응。방법장86례환자수궤분위량조，치료조여이감초산미주사액150mg，대조조조급여류보라저200mg。결과량조환자치료후림상증상、체정급간공능지표교치료전균유명현개선。결론이감초산미치료화료약물성간손해구유간공능회복쾌、불량반응소적우점，림상료효우우류보라저。
Objective To compare the clinical ef ect and adverse reactions of Magnesium Isoglycyrrhizzinate (MI)and Tiopronin (TP)on hepatic dysfunction induced by chemotherapeutic drugs. Methods 86 patients were randomly divided into two groups, the treatment group was given Magnesium Isoglycyrrhizinate Injection 150mg, control group treated with Tiopronin 200mg. Results After two weeks,the symptoms and liver function parameters of two groups were significantlY improved,No obvious adverse reactions were found in MI group. Conclusion The clinical ef ect of MI on hepatic dysfunction induced by chemotherapeutic drugs is bet er than that of TP.
