食品研究与开发
食品研究與開髮
식품연구여개발
FOOD RESEARCH AND CEVELOPMENT
2014年
3期
91-93
,共3页
密环菌多糖%D-氨基半乳糖%保肝
密環菌多糖%D-氨基半乳糖%保肝
밀배균다당%D-안기반유당%보간
Armillariella mellea polysaccharides%D-GalN%hepatoprotective
研究密环菌多糖对D-氨基半乳糖致肝细胞损伤的影响。D-氨基半乳糖诱导小鼠急性肝损伤,比色法测定血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、白蛋白(Alb)、谷胱甘肽S转移酶(GST)活力和肝组织超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的活性以及丙二醛(MDA)含量。密环菌多糖抑制急性肝损伤小鼠ALT、AST和GST活性的升高,并提高SOD、GSH-Px活力和ALB,同时显著降低MDA含量。密环菌多糖具有一定的肝保护作用,其机制可能与抗氧化作用有关。
研究密環菌多糖對D-氨基半乳糖緻肝細胞損傷的影響。D-氨基半乳糖誘導小鼠急性肝損傷,比色法測定血清丙氨痠氨基轉移酶(ALT)、天鼕氨痠氨基轉移酶(AST)、白蛋白(Alb)、穀胱甘肽S轉移酶(GST)活力和肝組織超氧化物歧化酶(SOD)、穀胱甘肽過氧化物酶(GSH-Px)的活性以及丙二醛(MDA)含量。密環菌多糖抑製急性肝損傷小鼠ALT、AST和GST活性的升高,併提高SOD、GSH-Px活力和ALB,同時顯著降低MDA含量。密環菌多糖具有一定的肝保護作用,其機製可能與抗氧化作用有關。
연구밀배균다당대D-안기반유당치간세포손상적영향。D-안기반유당유도소서급성간손상,비색법측정혈청병안산안기전이매(ALT)、천동안산안기전이매(AST)、백단백(Alb)、곡광감태S전이매(GST)활력화간조직초양화물기화매(SOD)、곡광감태과양화물매(GSH-Px)적활성이급병이철(MDA)함량。밀배균다당억제급성간손상소서ALT、AST화GST활성적승고,병제고SOD、GSH-Px활력화ALB,동시현저강저MDA함량。밀배균다당구유일정적간보호작용,기궤제가능여항양화작용유관。
To investigate the protective effects of polysaccharides from Armillariella mellea on injured liver induced by D-galactosamine (D-GalN). D-GalN was used to induce the liver injury in mice. The levels of ALT, AST, albumin and GST in serum, the activities of SOD, GSH-Px and MDA in liver homogenates were investigated using the colorimetric method. Armillariella mellea polysaccharides could reduce the elevated ALT , AST and GST, increase albumin content in serum of mice with liver injury, inhance the activities of SOD, GSH-Px, and decrease the elevated MDA concentration in liver. Armillariella mellea polysaccharides have the protective effects on the acute chemical liver injury in mice. The effects may be due to its antioxidant activity.