CAJ | 학술논문

目的：探讨非糖尿病腹膜透析患者糖化血红蛋白( HbAlc)水平与冠状动脉狭窄的相关性。方法：分析2011年1月至2013年7月在百色市人民医院进行持续不卧床腹膜透析治疗的38例非糖尿病成年慢性肾脏病患者的临床资料，按照有无冠状动脉狭窄将患者分为对照组(20例)和冠状动脉狭窄组(18例)。比较两组危险因素及检验指标的差异，分析冠状动脉狭窄的影响因素。结果：冠状动脉狭窄组的收缩压、FBG、2 hPBG、LDL-C、TC和HbAlc均高于对照组(P<0.05)。冠状动脉狭窄与年龄、收缩压、FBG、2 hPBG、LDL-C、TC、HbA1c呈正相关(P<0.05)，而HbAlc对冠状动脉狭窄的影响最大。结论：在非糖尿病腹膜透析患者中，HbAlc水平与冠状动脉狭窄呈正相关，HbAlc可能是冠状动脉狭窄的预测因子。
목적：탐토비당뇨병복막투석환자당화혈홍단백( HbAlc)수평여관상동맥협착적상관성。방법：분석2011년1월지2013년7월재백색시인민의원진행지속불와상복막투석치료적38례비당뇨병성년만성신장병환자적림상자료，안조유무관상동맥협착장환자분위대조조(20례)화관상동맥협착조(18례)。비교량조위험인소급검험지표적차이，분석관상동맥협착적영향인소。결과：관상동맥협착조적수축압、FBG、2 hPBG、LDL-C、TC화HbAlc균고우대조조(P<0.05)。관상동맥협착여년령、수축압、FBG、2 hPBG、LDL-C、TC、HbA1c정정상관(P<0.05)，이HbAlc대관상동맥협착적영향최대。결론：재비당뇨병복막투석환자중，HbAlc수평여관상동맥협착정정상관，HbAlc가능시관상동맥협착적예측인자。
Objective:To investigate the correlation between glycosylated hemoglobin ( HbA1c) and the magnitude of coronary artery stenosis in non-diabetes mellitus patients receiving abdominal dialysis. Methods:We analyzed the clinical profiles of 38 non-diabetic patients with chronic kidney disease who were receiving ambulatory abdominal dialysis in Baise People’ s Hospital between January 2011 and July 2013. Patients were further stratified to control group (n=20) and coronary artery stenosis group (n=18) for comparison on the risk fators and the clinical indices. Results:The coronary artery stenosis group yielded higher levels of systolic blood pressure, FBG, 2hPBG, LDL-C, TC and HbAlc than control group (all P<0. 05). The magnitude of coronary artery stenosis was positively correlated with the age, systolic blood pressure, FBG, 2hPBG, LDL-C, TC and HbA1c ( all P < 0. 05, in particular the level of HbAlc. Conclusion: In non-diabetic patients receiving abdominal dialysis, the level of HbAlc is positively correlated with the magnitude of coronary artery stenosis, suggesting that it is a predictor of coronary artery stenosis.