湖南师范大学学报（医学版）
湖南師範大學學報（醫學版）
호남사범대학학보（의학판）
JOURNAL OF HUNAN NORMAL UNIVERSITY(MEDICAL SCIENCE)
2013年
3期
51-52,55
,共3页
肖创清%蒋立%黄志红
肖創清%蔣立%黃誌紅
초창청%장립%황지홍
内皮抑素%细胞角蛋白19片段%肺癌
內皮抑素%細胞角蛋白19片段%肺癌
내피억소%세포각단백19편단%폐암
ES%CYFRA21-1%Lung Cancer
目的：探讨血清ES和CYFRA21-1在肺癌患者血清中的水平及其在预后上的意义。方法：分别用电化学发光免疫学分析法和ELISA法对96例肺癌患者化疗前后及100例健康人血清中的ES和CYFRA21-1含量进行测定。结果：肺癌患者血清中的ES和CYFRA21-1水平明显高于健康对照组，化疗后两者水平均显不同程度的下降。结论：血清ES和CYFRA21-1的测定对肺癌患者化疗后的病情评估预后判断有一定的临床意义。
目的：探討血清ES和CYFRA21-1在肺癌患者血清中的水平及其在預後上的意義。方法：分彆用電化學髮光免疫學分析法和ELISA法對96例肺癌患者化療前後及100例健康人血清中的ES和CYFRA21-1含量進行測定。結果：肺癌患者血清中的ES和CYFRA21-1水平明顯高于健康對照組，化療後兩者水平均顯不同程度的下降。結論：血清ES和CYFRA21-1的測定對肺癌患者化療後的病情評估預後判斷有一定的臨床意義。
목적：탐토혈청ES화CYFRA21-1재폐암환자혈청중적수평급기재예후상적의의。방법：분별용전화학발광면역학분석법화ELISA법대96례폐암환자화료전후급100례건강인혈청중적ES화CYFRA21-1함량진행측정。결과：폐암환자혈청중적ES화CYFRA21-1수평명현고우건강대조조，화료후량자수평균현불동정도적하강。결론：혈청ES화CYFRA21-1적측정대폐암환자화료후적병정평고예후판단유일정적림상의의。
Objective To evaluate the serum level of endostatin (ES) and CYFRA21-1 in patients with Lung cancer before and after cancer themotherapy and research its clinical applications. Methods The levels of ES and CYFRA21-1 were measured in 96 patients with pulmonary cancinoma before and after chemotherapy on 21th days and 100 healthy persons as controls, using chemolumin escence and ELISA methods respectively. Results The serum levels of ES and CYFRA21-1 in the cancer patients group were significantly higher than those healthy people.The amounts of ES and CYFRA21-1 in serum of lung cancer patients after chemotherapy were decreased. Conclusion The test on ES and CYFRA21-1 in serum of patients with lung cancer after chemotherapy has some clinical applications in disease evaluation and diagnosis judge.
