CAJ | 학술논문

目的：分析厦门大学附属中山医院近年来急性髓性白血病的发病情况与趋势，从中了解本地区急性髓性白血病的流行趋势，为制定科学的防治方法提供依据。方法回顾性分析2005～2012年厦门大学附属中山医院就诊的初发急性髓性白血病病例资料，统计分析年龄、性别、亚型及疗效的差异。结果新发急性髓性白血病患者的男女比例相当，无差异，25至59岁的中青年为高发病人群，其中35至39岁年龄段最高发，75到79岁出现老年人发病小高峰；M2、M3、M5是发病人数最多的三个亚型，且在未成年人、成年人、老年人不同年龄段组的发病比例有显著差异；2005～2012年新增患者人数具有上升趋势。结论2005～2012年本院新发急性髓性白血病人数呈上升趋势，不同年龄段新发病例疗效差异显著可能与疾病亚型相关。
목적：분석하문대학부속중산의원근년래급성수성백혈병적발병정황여추세，종중료해본지구급성수성백혈병적류행추세，위제정과학적방치방법제공의거。방법회고성분석2005～2012년하문대학부속중산의원취진적초발급성수성백혈병병례자료，통계분석년령、성별、아형급료효적차이。결과신발급성수성백혈병환자적남녀비례상당，무차이，25지59세적중청년위고발병인군，기중35지39세년령단최고발，75도79세출현노년인발병소고봉；M2、M3、M5시발병인수최다적삼개아형，차재미성년인、성년인、노년인불동년령단조적발병비례유현저차이；2005～2012년신증환자인수구유상승추세。결론2005～2012년본원신발급성수성백혈병인수정상승추세，불동년령단신발병례료효차이현저가능여질병아형상관。
Objective To explore the morbidity and trend of acute myeloid leukemia of Zhongshan Hospital Xiamen University in recent years, and to provide support for its prevention and intervention. Methods The retrospective analysis of acute myeloid leukemia patient of Zhongshan Hospital Xiamen University from 2005 to 2012 was made to analyze the differences among age, gender, subtype, and curative effect. Results The ratio of newly diagnosed acute myeloid leukemia between male and female was nearly same. The incidence of young and middle aged population between 25 to 59 years old was high. Among them, the highest incidence appeared in people aged 35 to 39. There was a small peak of incidence in old population aged 75 to 79. M2, M3, M5 were the most common subtypes of all patients, and there was a significant difference among age groups of minor, adult, and senior citizens. The newly diagnosed acute myeloid leukemia of each year was upward trend from 2005 to 2012. Conclusion The trend of newly diagnosed acute myeloid leukemia appeared upward. There was a significant difference of curative effects in newly diagnosed group of different ages may be caused by the specific subtype.