CAJ | 학술논문

目的：评价用超选择性肝动脉栓塞术（TAE）治疗多囊肝（PLD）的长期疗效和安全性。方法对23例有严重症状的PLD患者进行超选择性肝动脉栓塞术。患者女19例，男4例，年龄36.0～68.0岁，平均（49.3±3.4）岁。所有患者在TAE前后行上腹部CT平扫＋增强扫描：TAE后第3个月、第6个月及此后每间隔半年复查CT。结果23例患者共行27次介入治疗，手术技术成功率为100%，中位随访时间为19个月（3～58个月），2例无效，可供评价疗效者21例，有效率为91.2%。术前患者平均腹围为（105.7±8.1）cm，术后患者平均腹围为（95.2±6.7）cm，术前术后平均腹围具有统计学差异（P＜0.001）。平均腹围开始缩小时间（8.0±3.5）个月，症状改善时间（7.1±2.2）个月；栓塞后综合征多在栓塞术后7 d内缓解，在术后第6天及长期复查肝功能均在正常水平。结论 TAE治疗多囊肝，长期疗效可靠，安全性高，值得临床进一步推广应用。
목적：평개용초선택성간동맥전새술（TAE）치료다낭간（PLD）적장기료효화안전성。방법대23례유엄중증상적PLD환자진행초선택성간동맥전새술。환자녀19례，남4례，년령36.0～68.0세，평균（49.3±3.4）세。소유환자재TAE전후행상복부CT평소＋증강소묘：TAE후제3개월、제6개월급차후매간격반년복사CT。결과23례환자공행27차개입치료，수술기술성공솔위100%，중위수방시간위19개월（3～58개월），2례무효，가공평개료효자21례，유효솔위91.2%。술전환자평균복위위（105.7±8.1）cm，술후환자평균복위위（95.2±6.7）cm，술전술후평균복위구유통계학차이（P＜0.001）。평균복위개시축소시간（8.0±3.5）개월，증상개선시간（7.1±2.2）개월；전새후종합정다재전새술후7 d내완해，재술후제6천급장기복사간공능균재정상수평。결론 TAE치료다낭간，장기료효가고，안전성고，치득림상진일보추엄응용。
Objective To evaluate the safety and long-term efficacy of transcatheter super-selective hepatic arterial embolization (TAE) for patients with polycystic liver disease (PLD). Methods A total of 23 patients with symptomatic PLD were enrolled. The patients consisted of nineteen women and four men [aged 36.0-68.0 years, mean age(49.3±3.4)years]. All patients underwent contrast enhanced computed tomography (CT) scan of the liver before TAE and at every 3 months for the first half year after TAE, and at 6-monthly intervals thereafter. Results Follow-up was performed at a median of 19 months (range 3-58 months). 23 cases were treated by intervention 27 times, All procedures were successful without serious complications. TAE failed to benefit in 2 patients, but there were no complaints of worsening of the symptoms. available for 21 patients evaluable for efficacy, effective rate of 91.2%. The average preoperative abdominal circumference was (105.7± 8.1)cm, the average postoperative abdominal circumference was(95.2±6.7)cm. After treatment average abdominal circumference reduction 10.1 cm (3.0-21.0 cm), statistically significant (P<0.001). After treatment average abdominal circumference began to reduce time[(7.0±3.5)mon], symptoms improved time [(9.1±4.2)mon]. Embolization syndrome returned to the normal range within 1-7 day in all patients. Conclusion Transcatheter super-selective hepatic arterial embolization for patients with polycystic liver disease is a safe and long-term effective treatment for PLD patients. worthy of further clinical expand the application.