中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
11期
1643-1645
,共3页
有机磷农药%中毒%呼吸衰竭%机械通气
有機燐農藥%中毒%呼吸衰竭%機械通氣
유궤린농약%중독%호흡쇠갈%궤계통기
Organophosphate pesticides%Poisoning%Respiratory failure%Mechanical ventilation
目的 探讨机械通气治疗急性重度有机磷农药中毒呼吸衰竭的时机.方法 将115例急性重度有机磷农药中毒呼吸衰竭患者,根据机械通气不同指征分为观察组A40例、观察组B 38例、对照组37例.对三组治愈率、吸入性肺炎发生率、机械通气时间、住院时间进行统计学分析.结果 观察组A治愈率(97.5％)明显高于对照组(83.4％)和观察组B(92.1％)(P＜0.05或P＜0.01)；观察组A吸入性肺炎(2例)明显少于对照组(8例)(P＜0.05)；观察组A、观察组B住院时间[(4.46±0.51)d、(7.11±0.83)d]和机械通气时间[(55.40±5.24)h、(79.47±2.44)h]均明显短于对照组[(10.40±1.12)d、(100.30±2.15)h](均P＜0.01)；观察组A住院时间[(4.46±0.51)d]和机械通气时间[(55.40±5.24) h]均明显短于观察组B[(7.11±0.83)d、(79.47±2.44)h](均P＜0.01).结论 呼吸频率≥30次/min＜ 34次/min或≤10次/min,或自主呼吸减弱,血气分析提示低氧血症(60 mm Hg＜ PaO2≤70 mm Hg)是机械通气治疗急性重度有机磷农药中毒呼吸衰竭的最佳时机.
目的 探討機械通氣治療急性重度有機燐農藥中毒呼吸衰竭的時機.方法 將115例急性重度有機燐農藥中毒呼吸衰竭患者,根據機械通氣不同指徵分為觀察組A40例、觀察組B 38例、對照組37例.對三組治愈率、吸入性肺炎髮生率、機械通氣時間、住院時間進行統計學分析.結果 觀察組A治愈率(97.5％)明顯高于對照組(83.4％)和觀察組B(92.1％)(P＜0.05或P＜0.01)；觀察組A吸入性肺炎(2例)明顯少于對照組(8例)(P＜0.05)；觀察組A、觀察組B住院時間[(4.46±0.51)d、(7.11±0.83)d]和機械通氣時間[(55.40±5.24)h、(79.47±2.44)h]均明顯短于對照組[(10.40±1.12)d、(100.30±2.15)h](均P＜0.01)；觀察組A住院時間[(4.46±0.51)d]和機械通氣時間[(55.40±5.24) h]均明顯短于觀察組B[(7.11±0.83)d、(79.47±2.44)h](均P＜0.01).結論 呼吸頻率≥30次/min＜ 34次/min或≤10次/min,或自主呼吸減弱,血氣分析提示低氧血癥(60 mm Hg＜ PaO2≤70 mm Hg)是機械通氣治療急性重度有機燐農藥中毒呼吸衰竭的最佳時機.
목적 탐토궤계통기치료급성중도유궤린농약중독호흡쇠갈적시궤.방법 장115례급성중도유궤린농약중독호흡쇠갈환자,근거궤계통기불동지정분위관찰조A40례、관찰조B 38례、대조조37례.대삼조치유솔、흡입성폐염발생솔、궤계통기시간、주원시간진행통계학분석.결과 관찰조A치유솔(97.5％)명현고우대조조(83.4％)화관찰조B(92.1％)(P＜0.05혹P＜0.01)；관찰조A흡입성폐염(2례)명현소우대조조(8례)(P＜0.05)；관찰조A、관찰조B주원시간[(4.46±0.51)d、(7.11±0.83)d]화궤계통기시간[(55.40±5.24)h、(79.47±2.44)h]균명현단우대조조[(10.40±1.12)d、(100.30±2.15)h](균P＜0.01)；관찰조A주원시간[(4.46±0.51)d]화궤계통기시간[(55.40±5.24) h]균명현단우관찰조B[(7.11±0.83)d、(79.47±2.44)h](균P＜0.01).결론 호흡빈솔≥30차/min＜ 34차/min혹≤10차/min,혹자주호흡감약,혈기분석제시저양혈증(60 mm Hg＜ PaO2≤70 mm Hg)시궤계통기치료급성중도유궤린농약중독호흡쇠갈적최가시궤.
Objective To explore the treatment opportunity of mechanical ventilation for acute severe organophosphorus pesticide poisoning patients with respiratory failure.Methods According to the different indications of mechanical ventilation,115 acute severe organophosphorus pesticide poisoning patients with respiratory failure were divided into the observation group A (40 cases),the observation group B(38 cases)and the control group(37 cases).The cure rate,aspiration pneumonia incidence,duration of mechanical ventilation,length of hospital stay of the three groups were analyzed.Results The cure rate of the observation group A(97.5％) was significantly higher than that of the control group(83.4％)and the observation group B (92.1％) (P ＜ 0.05 or P ＜ 0.01) ;The aspiration pneumonia of the observation group(2 cases) was significantly less than that of the control group(8 cases)(P ＜ 0.05) ;The hospitalization time [(4.46 ± 0.51) d,(7.11 ± 0.83) d] and the duration of mechanical ventilation [(55.40 ± 5.24)h,(79.47 ± 2.44) h] of the observation group A and the observation group B were significantly shorter than those of the control group [(10.40 ± 1.12) d,(100.30 ± 2.15) h] (all P ＜ 0.01) ; The hospitalization time and the duration of mechanical ventilation of the observation group A [(4.46 ± 0.51) d,(55.40 ± 5.24) h] were significantly shorter than those of the observation group B [(7.11 ± 0.83)d,(79.47 ± 2.44)h] (all P ＜ 0.01).Conclusion Respiratory rate ≥30 times/min and ＜ 34 times/min or ≤ 10 times/min,or spontaneous breathing weakened,and blood gas analysis prompted hypoxemia(60 mm Hg ＜ PaO2 ≤ 70 mm Hg)is best opportunity of mechanical ventilation for acute severe organophosphorus pesticide poisoning patients with respiratory failure.
