CAJ | 학술논문

针对现场电化学测试中电化学工作站携带不便、供电困难等问题，设计了一种基于核酸适体生物传感器的便携式循环伏安测试系统。该系统采用实验室研发制备的核酸适体生物传感器设计了锁定放大电路、恒电位电路及相敏检测程序，可实现微弱信号提取，从而有效克服电路系统噪声。实验结果表明，该系统能实现循环伏安测试，具有较高的信噪比，测试精度达到1μA，省电、操作简单，能够满足现场快速准确地进行循环伏安测试的需要。
침대현장전화학측시중전화학공작참휴대불편、공전곤난등문제，설계료일충기우핵산괄체생물전감기적편휴식순배복안측시계통。해계통채용실험실연발제비적핵산괄체생물전감기설계료쇄정방대전로、항전위전로급상민검측정서，가실현미약신호제취，종이유효극복전로계통조성。실험결과표명，해계통능실현순배복안측시，구유교고적신조비，측시정도체도1μA，성전、조작간단，능구만족현장쾌속준학지진행순배복안측시적수요。
Aiming at the problem of inconvenience to carry and difficulty with power in-field electrochemi-cal measurement,a portable cyclic voltammetry measurement system was designed based on aptamer-based biosensor developed by our laboratory.For overcoming the noise in the circuits effectively,a lock-in ampli-fier,potentiostat and program for phase sensitive detection were designed to extract weak signal.Experiment results showed that the system could implement cyclic voltammetry,which had higher SNR(signal noise ra-tio),the measurement precision of which could reach 1 μA.It had features of power saving,and simple era-tion,which could meet the requirement of in-field cyclic voltammetry measurement.