中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
1期
194-196
,共3页
多囊卵巢综合征%二甲双胍%达英-35
多囊卵巢綜閤徵%二甲雙胍%達英-35
다낭란소종합정%이갑쌍고%체영-35
Polycystic ovary syndrome%Metformin%Dyne-35
目的：探讨二甲双胍联合达英-35治疗多囊卵巢综合征（PCOS）的疗效。方法对96例POCS患者给予口服二甲双胍和达英-35，连续服用3个月。观察治疗前后临床症状、性激素、血糖、胰岛素和卵巢的变化情况。结果治疗后患者临床表现改善明显；61例患者的卵巢多囊性改变明显；性激素中LH和T较治疗前均显著下降，差异有统计学意义（P＜0.01），FSH、P、PRL、E2则无明显差异（P＞0.05）；治疗前后空腹血糖水平无明显差异（P＞0.05）；治疗后患者胰岛素水平较治疗前有明显下降（P＜0.05）。结论二甲双胍联合达英-35治疗PCOS的疗效显著。
目的：探討二甲雙胍聯閤達英-35治療多囊卵巢綜閤徵（PCOS）的療效。方法對96例POCS患者給予口服二甲雙胍和達英-35，連續服用3箇月。觀察治療前後臨床癥狀、性激素、血糖、胰島素和卵巢的變化情況。結果治療後患者臨床錶現改善明顯；61例患者的卵巢多囊性改變明顯；性激素中LH和T較治療前均顯著下降，差異有統計學意義（P＜0.01），FSH、P、PRL、E2則無明顯差異（P＞0.05）；治療前後空腹血糖水平無明顯差異（P＞0.05）；治療後患者胰島素水平較治療前有明顯下降（P＜0.05）。結論二甲雙胍聯閤達英-35治療PCOS的療效顯著。
목적：탐토이갑쌍고연합체영-35치료다낭란소종합정（PCOS）적료효。방법대96례POCS환자급여구복이갑쌍고화체영-35，련속복용3개월。관찰치료전후림상증상、성격소、혈당、이도소화란소적변화정황。결과치료후환자림상표현개선명현；61례환자적란소다낭성개변명현；성격소중LH화T교치료전균현저하강，차이유통계학의의（P＜0.01），FSH、P、PRL、E2칙무명현차이（P＞0.05）；치료전후공복혈당수평무명현차이（P＞0.05）；치료후환자이도소수평교치료전유명현하강（P＜0.05）。결론이갑쌍고연합체영-35치료PCOS적료효현저。
Objective To investigate the therapeutic effects of metformin and Dyne - 35 for polycystic ovary syndrome (PCOS). Methods 96 patients with PCOS were studied. The changes of Clinical symptoms,Sex hormones, blood glucose,insulin,and ovaries were examined and compared Before and after treated with metformin and Dyne-35 for 3months. Results After treatment,Clinical symptoms improved obviously;61 cases of patients with polycystic ovary changed obviously;The serum luteinizing hormone(LH) and testosterone(T) were decreased,showing statistical difference(P<0.01),but FSH,P,PRL and E2 had no change(P>0.05);Further analysis showed that before treatment and after treatment the differences of Insulin level were significant(P<0.01). Conclusion Satisfactory effect could achieved by using Metformin and Dyne-35 for polycystic ovary syndrome (PCOS).
