中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
1期
91-93
,共3页
西酞普兰%脑卒中%抑郁症%疗效
西酞普蘭%腦卒中%抑鬱癥%療效
서태보란%뇌졸중%억욱증%료효
Citalopram%Stroke%Depression%Clinical effect
目的：探讨西酞普兰治疗脑卒中后抑郁症的临床疗效。方法将60例脑卒中后抑郁症患者随机分为研究组（西酞普兰组）和对照组（多虑平组）。研究组每日晨服西酞普兰20mg；对照组口服多虑平25mg 每日3次。两组连续服用4周。结果治疗4周后，研究组抑郁症的总有效率为93.3%，神经功能缺损的有效率93.4%；对照组抑郁症的有效率56.7%，神经功能缺损的有效率73.3%。两组间差异有统计学意义。结论西酞普兰能有效缓解脑卒中后抑郁症症状，对神经功能缺损的恢复有较大帮助，值得在临床上进一步推广。
目的：探討西酞普蘭治療腦卒中後抑鬱癥的臨床療效。方法將60例腦卒中後抑鬱癥患者隨機分為研究組（西酞普蘭組）和對照組（多慮平組）。研究組每日晨服西酞普蘭20mg；對照組口服多慮平25mg 每日3次。兩組連續服用4週。結果治療4週後，研究組抑鬱癥的總有效率為93.3%，神經功能缺損的有效率93.4%；對照組抑鬱癥的有效率56.7%，神經功能缺損的有效率73.3%。兩組間差異有統計學意義。結論西酞普蘭能有效緩解腦卒中後抑鬱癥癥狀，對神經功能缺損的恢複有較大幫助，值得在臨床上進一步推廣。
목적：탐토서태보란치료뇌졸중후억욱증적림상료효。방법장60례뇌졸중후억욱증환자수궤분위연구조（서태보란조）화대조조（다필평조）。연구조매일신복서태보란20mg；대조조구복다필평25mg 매일3차。량조련속복용4주。결과치료4주후，연구조억욱증적총유효솔위93.3%，신경공능결손적유효솔93.4%；대조조억욱증적유효솔56.7%，신경공능결손적유효솔73.3%。량조간차이유통계학의의。결론서태보란능유효완해뇌졸중후억욱증증상，대신경공능결손적회복유교대방조，치득재림상상진일보추엄。
Objective To explore the Clinical effect of citalopram in treatment of post-stroke depression. Methods Sixty patients with post-stoke depression were randomly divided into study group(citalopram group) and the control group(doxepin group).Study group every morning 20mg oral citalopram.Control group oral doxepin 25mg three times a day. Both groups were taken for 4 weeks. Results The total effective for treatment of depression the study group is 93.3%,neurologic impairment of the total effective is 93.4%.The total effective for treatment of depression the control group is 56.7%,neurologic impairment of the total effective is 73.3%.A statistically significant difference between the two groups. Conclusion Citalopram can effectively alleviate the symptoms of post-stroke depression,neurologic recovery will be of great help and worth in clinical practice to further promote.
