CAJ | 학술논문

目的：分析在晚期非小细胞肺癌的临床治疗中应用厄洛替尼的临床疗效、毒副反应等。方法从2009年4月～2013年4月期间收治的晚期非小细胞肺癌患者中选取30例作为研究对象，并给予患者应用厄洛替尼进行治疗，若患者出现病变进展、无法耐受的毒副反应，则终止治疗，期间观察患者在应用该药物后的疗效、毒副反应等。结果研究发现，30例晚期非小细胞肺癌患者，11例患者疾病进展（PD），12例患者疾病稳定（SD），7例患者部分缓解（PR），0例患者完全缓解（CR），治疗有效例数为7例，占总人数的23.33%。在毒副反应方面，患者在用药后，主要有恶心呕吐、腹泻、皮肤瘙痒以及皮疹等，程度均不严重，通过相应的治疗后得到缓解。结论在晚期非小细胞肺癌患者的临床治疗中应用厄洛替尼，有明显的疗效，且毒副反应较为轻微。
목적：분석재만기비소세포폐암적림상치료중응용액락체니적림상료효、독부반응등。방법종2009년4월～2013년4월기간수치적만기비소세포폐암환자중선취30례작위연구대상，병급여환자응용액락체니진행치료，약환자출현병변진전、무법내수적독부반응，칙종지치료，기간관찰환자재응용해약물후적료효、독부반응등。결과연구발현，30례만기비소세포폐암환자，11례환자질병진전（PD），12례환자질병은정（SD），7례환자부분완해（PR），0례환자완전완해（CR），치료유효례수위7례，점총인수적23.33%。재독부반응방면，환자재용약후，주요유악심구토、복사、피부소양이급피진등，정도균불엄중，통과상응적치료후득도완해。결론재만기비소세포폐암환자적림상치료중응용액락체니，유명현적료효，차독부반응교위경미。
Objective To analyze the clinical treatment of advanced non-small cell lung cancer in the application for it's clinical curative effect, adverse reaction and so on. Methods from April 2009 to April 2009 in patients with advanced non-small cell lung cancer treated during selecting 30 cases as the research object, and to give patients used it for treatment,if patients lesions appears on the horizon,can't tolerate the side reaction of,end treatment,after the application of the drug were observed during the period of efficacy,adverse reaction,etc. Results The study found that 30 cases of advanced non-small cell lung cancer patients,11 patients with disease progression (PD),12 patients had stable disease (SD),7 cases of patients with partial response (PR),and 0 cases with complete remission (CR),effective treatment cases in 7 cases,accounting for 23.33% of the total. In terms of adverse reactions,patients after medication,there are mainly nausea and vomiting,diarrhea,itching and rash,etc.,were serious degree,through the appropriate ease after treatment. Conclusion In the clinical treatment of patients with advanced non-small cell lung cancer in the application,for it has obvious curative effect,and side reaction was mild.