心脑血管病防治
心腦血管病防治
심뇌혈관병방치
PREVENTION AND TREATMENT OF CARDIO-CEREBRAL-VASCULAR DISEASE
2014年
1期
11-12,26
,共3页
冠状动脉粥样硬化性心脏病%冠状动脉造影%纤维蛋白原%糖化血红蛋白
冠狀動脈粥樣硬化性心髒病%冠狀動脈造影%纖維蛋白原%糖化血紅蛋白
관상동맥죽양경화성심장병%관상동맥조영%섬유단백원%당화혈홍단백
Coronary atherosclerotic heart disease%Coronary angiography%Fibrinogen%Glycosylated hemoglobin
目的:分析血液纤维蛋白原和糖化血红蛋白水平与冠状动脉Gensini积分之间的相关性。方法回顾分析261例行冠状动脉造影及相关实验室检查的患者,根据Gensini积分及冠状动脉内径狭窄程度将患者分为A组(对照组,狭窄<50%,共46例),B组(冠状动脉狭窄≥50%,Gensini积分<20,共122例)、C组(冠状动脉狭窄≥50%, Gensini积分≥20,共93例),分析3组间血液纤维蛋白原和糖化血红蛋白等指标与Gensini积分的相关性。结果 A、B、C三组的血液纤维蛋白原、糖化血红蛋白、同型半胱氨酸、尿酸浓度均依次增高,差异有统计学意义(均 P<0.05);215例冠心病的纤维蛋白原和糖化血红蛋白与Gensini积分间均呈正相关(r=0.17、0.15,P<0.05)。结论血液纤维蛋白原和糖化血红蛋白浓度越高,冠状动脉狭窄越严重,可用于冠心病的早期危险性评估。
目的:分析血液纖維蛋白原和糖化血紅蛋白水平與冠狀動脈Gensini積分之間的相關性。方法迴顧分析261例行冠狀動脈造影及相關實驗室檢查的患者,根據Gensini積分及冠狀動脈內徑狹窄程度將患者分為A組(對照組,狹窄<50%,共46例),B組(冠狀動脈狹窄≥50%,Gensini積分<20,共122例)、C組(冠狀動脈狹窄≥50%, Gensini積分≥20,共93例),分析3組間血液纖維蛋白原和糖化血紅蛋白等指標與Gensini積分的相關性。結果 A、B、C三組的血液纖維蛋白原、糖化血紅蛋白、同型半胱氨痠、尿痠濃度均依次增高,差異有統計學意義(均 P<0.05);215例冠心病的纖維蛋白原和糖化血紅蛋白與Gensini積分間均呈正相關(r=0.17、0.15,P<0.05)。結論血液纖維蛋白原和糖化血紅蛋白濃度越高,冠狀動脈狹窄越嚴重,可用于冠心病的早期危險性評估。
목적:분석혈액섬유단백원화당화혈홍단백수평여관상동맥Gensini적분지간적상관성。방법회고분석261례행관상동맥조영급상관실험실검사적환자,근거Gensini적분급관상동맥내경협착정도장환자분위A조(대조조,협착<50%,공46례),B조(관상동맥협착≥50%,Gensini적분<20,공122례)、C조(관상동맥협착≥50%, Gensini적분≥20,공93례),분석3조간혈액섬유단백원화당화혈홍단백등지표여Gensini적분적상관성。결과 A、B、C삼조적혈액섬유단백원、당화혈홍단백、동형반광안산、뇨산농도균의차증고,차이유통계학의의(균 P<0.05);215례관심병적섬유단백원화당화혈홍단백여Gensini적분간균정정상관(r=0.17、0.15,P<0.05)。결론혈액섬유단백원화당화혈홍단백농도월고,관상동맥협착월엄중,가용우관심병적조기위험성평고。
Objective To investigate the relationship between Gensini scores of coronary artery and blood fibrinogen and glycosylated hemoglobin.Methods 261 patients with coronary artery angiography and related laboratory inspection were analyzed retrospectively , according to Gensini scores and the stenosis degree of coronary artery ,they were divided into group A (control group ,stenosis degree of coronary artery <50% ,n=46 ) ,group B (stenosis degree of coronary artery≥50% ,Gensini scores<20 ,n=122 ) and group C (stenosis degree of coronary artery≥50% ,Gensini scores≥20 ,n=93) ,then analyzed the relationship between Gensini scores , blood fibrinogen and glycosylated hemoglobin. Results 1.The blood fibrinogen of group C was higher than group B ,group B was higher than group A( P<0.05) ,and it had the same situation for glycosylated hemoglobin ,homocysteine ,and uric acid.2.There was a significant positive correlation between Gensini scores with blood fibrinogen ,glycosylated hemoglobin in 215 cases ( r=0.17 , 0.15 , P<0.05).Conclusions The higher the blood concentration of fibrinogen and glycosylated hemoglobin ,the more severe the degree of coronary artery stenosis is.The index can be used to assess the early risk of coronary atherosclerotic heart disease.