CAJ | 학술논문

目的：分析小儿肺炎支原体（MP）感染所致肺外并发症的临床特征及出现并发症的危险因素。方法研究2009年6月~2013年6月于我院儿科住院的120例MP感染导致肺外并发症的患儿，分析其临床特征，并与同期确诊为MP感染但无并发症的患儿192例进行对比分析。结果 MP感染可引起肺外不同脏器、系统损害，消化系统并发症发生率最高，泌尿系统、血液系统、心血管系统、神经系统、皮肤与关节等均可出现损害。出现肺外并发症组患儿与未出现并发症组比较，前者的热程较后者长，差异有统计学意义（P＜0.05），前者胸片出现肺不张及大片状阴影改变的机率明显高于后者（P＜0.05），出现肺外并发症的患儿，经大环内酯类抗生素及对症治疗后可获痊愈。结论小儿MP感染可引起多系统、脏器损害，临床表现多样，应引起临床医生的重视，避免误诊，及早确诊、治疗，预后好。
목적：분석소인폐염지원체（MP）감염소치폐외병발증적림상특정급출현병발증적위험인소。방법연구2009년6월~2013년6월우아원인과주원적120례MP감염도치폐외병발증적환인，분석기림상특정，병여동기학진위MP감염단무병발증적환인192례진행대비분석。결과 MP감염가인기폐외불동장기、계통손해，소화계통병발증발생솔최고，비뇨계통、혈액계통、심혈관계통、신경계통、피부여관절등균가출현손해。출현폐외병발증조환인여미출현병발증조비교，전자적열정교후자장，차이유통계학의의（P＜0.05），전자흉편출현폐불장급대편상음영개변적궤솔명현고우후자（P＜0.05），출현폐외병발증적환인，경대배내지류항생소급대증치료후가획전유。결론소인MP감염가인기다계통、장기손해，림상표현다양，응인기림상의생적중시，피면오진，급조학진、치료，예후호。
Objective To analyze the clinical features of Mycoplasma pneumonia (MP) infection induced extrapulmonary complications in children and the risk factors of complications. Methods 120 children with MP infection induced extrapulmonary complications who hospitalized in our hospital from June 2009 to June 2013 were selected and their clinical features were analyzed. These children were compared to 192 MP infection children without extrapulmonary infection who were diagnosed in the corresponding period. Results MP infection could induce various extrapulmonary organ and system damage, of which the incidence of digestive system complications was the highest, and urinary system, blood system, cardiovascular system, nervous system, skin and joint damage might occur. Compared to the group without extrpulmonary complications,the group with extrpulmonary complications had longer fever duration,with significant difference (P < 0.05), and significantly higher incidences of pulmonary atelectasis and large shadow change(P < 0.05). The children with extrpulmonary complications fully recovered after macrolide antibiotics and symptomatic treatment. Conclusion MP infection in children can induce multiple system and organ damage and show various clinical manifestations, which should draw the clinical physicians' attention in order to avoid misdiagnosis;Timely diagnosis and treatment promise good prognosis.