CAJ | 학술논문

负压创面疗法处理临床上各种创面均具有显著效果。对其作用机制的研究有助于指导正确应用及进一步改进。本文综述了近些年负压创面疗法作用机制研究的最新进展。被广泛接受的机制包括收缩创面、稳定局部环境、减轻水肿和清除渗出物、增加血流灌注和促进肉芽组织形成等，而细菌清除和抗菌作用方面的机制尚存争议。
부압창면요법처리림상상각충창면균구유현저효과。대기작용궤제적연구유조우지도정학응용급진일보개진。본문종술료근사년부압창면요법작용궤제연구적최신진전。피엄범접수적궤제포괄수축창면、은정국부배경、감경수종화청제삼출물、증가혈류관주화촉진육아조직형성등，이세균청제화항균작용방면적궤제상존쟁의。
Negative-pressure wound therapy (NPWT) exerts a significant effect on different wounds. Studies on its mechanisms contribute to its correct application and further improvement. Following is a review of the update advances in its mechanisms. NPWT can reduce the wound surface area, stabilize the wound environment, alleviate wound edema, remove wound exudates, increase blood flow, and promote granulation tissue formation, which are the widely accepted mechanisms of NPWT. However, it is still controversial on its antimicrobial efficacy and bacterial clearance.