河北医学
河北醫學
하북의학
HEBEI MEDICINE
2014年
8期
1324-1327
,共4页
经皮冠状动脉介入术%急性冠状动脉综合征%替罗非班%临床疗效
經皮冠狀動脈介入術%急性冠狀動脈綜閤徵%替囉非班%臨床療效
경피관상동맥개입술%급성관상동맥종합정%체라비반%림상료효
PCI%ACS%Tirofiban%Clinical efficacy
目的：探讨分析在实施经皮冠状动脉介入（ PCI）治疗中应用替罗非班的治疗效果及其临床价值。方法：选取2011年7月至2013年9月收治拟行PCI治疗的急性冠状动脉综合征（ ACS）患者54例，根据就诊顺序随机分为观察组与对照组，对照组常规实施PCI治疗，观察组在实施PCI术前后输注替罗非班进行联合治疗，对比观察两组患者临床疗效，分析替罗非班在PCI中的应用价值。结果：观察组患者TIMI校正帧计数指标明显改善，左室射血分数与心输出量明显提高，且其改变程度均明显高于对照组（ P＜0．05）；观察组患者治疗后冠脉TIMI血流分级明显优于对照组，不良心脏事件明显少于对照组，P＜0．05，差异有统计学意义。结论：在临床实施PCI术过程中应用替罗非班联合治疗，能够有效改善冠状动脉血流情况，促进左心室收缩功能恢复，提高心肌灌注，减少不良心脏事件，配合PCI使用具有更为理想的临床疗效。
目的：探討分析在實施經皮冠狀動脈介入（ PCI）治療中應用替囉非班的治療效果及其臨床價值。方法：選取2011年7月至2013年9月收治擬行PCI治療的急性冠狀動脈綜閤徵（ ACS）患者54例，根據就診順序隨機分為觀察組與對照組，對照組常規實施PCI治療，觀察組在實施PCI術前後輸註替囉非班進行聯閤治療，對比觀察兩組患者臨床療效，分析替囉非班在PCI中的應用價值。結果：觀察組患者TIMI校正幀計數指標明顯改善，左室射血分數與心輸齣量明顯提高，且其改變程度均明顯高于對照組（ P＜0．05）；觀察組患者治療後冠脈TIMI血流分級明顯優于對照組，不良心髒事件明顯少于對照組，P＜0．05，差異有統計學意義。結論：在臨床實施PCI術過程中應用替囉非班聯閤治療，能夠有效改善冠狀動脈血流情況，促進左心室收縮功能恢複，提高心肌灌註，減少不良心髒事件，配閤PCI使用具有更為理想的臨床療效。
목적：탐토분석재실시경피관상동맥개입（ PCI）치료중응용체라비반적치료효과급기림상개치。방법：선취2011년7월지2013년9월수치의행PCI치료적급성관상동맥종합정（ ACS）환자54례，근거취진순서수궤분위관찰조여대조조，대조조상규실시PCI치료，관찰조재실시PCI술전후수주체라비반진행연합치료，대비관찰량조환자림상료효，분석체라비반재PCI중적응용개치。결과：관찰조환자TIMI교정정계수지표명현개선，좌실사혈분수여심수출량명현제고，차기개변정도균명현고우대조조（ P＜0．05）；관찰조환자치료후관맥TIMI혈류분급명현우우대조조，불양심장사건명현소우대조조，P＜0．05，차이유통계학의의。결론：재림상실시PCI술과정중응용체라비반연합치료，능구유효개선관상동맥혈류정황，촉진좌심실수축공능회복，제고심기관주，감소불양심장사건，배합PCI사용구유경위이상적림상료효。
Objective:To observe and analyze the effect and clinical value of tirofiban in treating percu-taneous coronary intervention .Method:54 cases with ACS treated with PCI in our hospital from July 2011 to September 2013 were selected and divided into two groups , the observation group and the control group .The control group was treated with conventional PCI , based on which the observation group received infusion of tirofiban before and after PCI operation .The clinical efficacy of two groups was compared and observed , and the application value of tirofiban to PCI was analyzed .Result:TIMI corrected frame count of the observation group improved evidently , left ventricular ejection fraction and cardiac output increased evidently , and the improvement degree was evidently higher than that of the control group (P<0.05).After treatment, coronary TIMI of the observation group was evidently better than that of the control group , and the adverse cardiac e-vents were evidently less than that of the control group ,P<0.05,which had statistical significance .Conclu-sion:Applying tirofiban in PCI operation not only can evidently improve coronary arterial blood flow , pro-mote the recovery of left ventricular systolic function , but also can improve myocardial perfusion and reduce adverse cardiac events , which has ideal clinical efficacy in combination with PCI .
