中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
5期
1-2
,共2页
芪参益气滴丸%糖尿病性心脏病%心功能不全
芪參益氣滴汍%糖尿病性心髒病%心功能不全
기삼익기적환%당뇨병성심장병%심공능불전
Qishen Yiqi pills%Diabetes heart disease%Heart failure
目的：观察芪参益气滴丸（天津天士力制药股份有限公司生产）对糖尿病性心脏病合并心功能不全的治疗作用。方法：选择入住我院的2012-2013年糖尿病性心脏病合并心功能不全患者88例，随机分成常规治疗组（对照组）和芪参益气滴丸组（治疗组），对照组给予降糖、降脂，强心、利尿、扩血管、抑制心肌重构等抗心衰治疗，治疗组在对照组基础上给予口服芪参益气滴丸，服药时间3个月，分别于服药前及服药后3个月后检查血脂、血糖、C反应蛋白、心钠素（BNP）及心脏超声，左室舒张末期内径（LVDd）、左室舒张末期容积（LVEDV）、左室收缩末期容积（LVESV）左室射血分数（LVEF）结果：经3个月治疗后，芪参益气滴丸治疗组LVDd、LVEDV、LVESV较对照组减低，差异显著（P<0.05），血浆BNP水平较对照组降低（P<0.05），左室射血分数明显提高（P<0.05），C反应蛋白水平明显降低。结论：在常规治疗的基础上加用芪参益气滴丸治疗糖尿病性心脏病合并心功能不全，能改善整体左室功能，具有一定的抗心室重构作用。能明显降低血浆BNP的水平，更好地改善心脏功能。
目的：觀察芪參益氣滴汍（天津天士力製藥股份有限公司生產）對糖尿病性心髒病閤併心功能不全的治療作用。方法：選擇入住我院的2012-2013年糖尿病性心髒病閤併心功能不全患者88例，隨機分成常規治療組（對照組）和芪參益氣滴汍組（治療組），對照組給予降糖、降脂，彊心、利尿、擴血管、抑製心肌重構等抗心衰治療，治療組在對照組基礎上給予口服芪參益氣滴汍，服藥時間3箇月，分彆于服藥前及服藥後3箇月後檢查血脂、血糖、C反應蛋白、心鈉素（BNP）及心髒超聲，左室舒張末期內徑（LVDd）、左室舒張末期容積（LVEDV）、左室收縮末期容積（LVESV）左室射血分數（LVEF）結果：經3箇月治療後，芪參益氣滴汍治療組LVDd、LVEDV、LVESV較對照組減低，差異顯著（P<0.05），血漿BNP水平較對照組降低（P<0.05），左室射血分數明顯提高（P<0.05），C反應蛋白水平明顯降低。結論：在常規治療的基礎上加用芪參益氣滴汍治療糖尿病性心髒病閤併心功能不全，能改善整體左室功能，具有一定的抗心室重構作用。能明顯降低血漿BNP的水平，更好地改善心髒功能。
목적：관찰기삼익기적환（천진천사력제약고빈유한공사생산）대당뇨병성심장병합병심공능불전적치료작용。방법：선택입주아원적2012-2013년당뇨병성심장병합병심공능불전환자88례，수궤분성상규치료조（대조조）화기삼익기적환조（치료조），대조조급여강당、강지，강심、이뇨、확혈관、억제심기중구등항심쇠치료，치료조재대조조기출상급여구복기삼익기적환，복약시간3개월，분별우복약전급복약후3개월후검사혈지、혈당、C반응단백、심납소（BNP）급심장초성，좌실서장말기내경（LVDd）、좌실서장말기용적（LVEDV）、좌실수축말기용적（LVESV）좌실사혈분수（LVEF）결과：경3개월치료후，기삼익기적환치료조LVDd、LVEDV、LVESV교대조조감저，차이현저（P<0.05），혈장BNP수평교대조조강저（P<0.05），좌실사혈분수명현제고（P<0.05），C반응단백수평명현강저。결론：재상규치료적기출상가용기삼익기적환치료당뇨병성심장병합병심공능불전，능개선정체좌실공능，구유일정적항심실중구작용。능명현강저혈장BNP적수평，경호지개선심장공능。
Objective: To observe the effect of Qishen Yiqi drop pills (Tianjin Tasly pharmaceutical Limited by Share Ltd) on treating diabetes heart disease with heart failure. Methods:From 2012 to 2013, 78 patients with diabetes heart disease with heart failure in our hospital were randomly divided into conventional treatment group (control group) and Qishen Yiqi pills group (treated group), the control group was given hypoglycemic, lipid-lowering, strong heart, diuretic, vasodilator, inhibiting myocardial reconstruction and other anti heart failure treatment, the treated group was given oral Qishen Yiqi pills more, taking time for 3 months, respectively before treatment and after treatment for 3 months after the blood fat, blood sugar, C reactive protein, atrial natriuretic peptide (BNP) and echocardiography, left ventricular end diastolic diameter (LVDd), left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV) and left ventricular ejection fraction (LVEF). Results: After 3 months after treatment, Qishen Yiqi pills group LVDd, LVEDV, LVESV lower than the control group, the difference was significant (P<0.05), the plasma BNP level was lower than control group (P<0.05), LVEF was significantly increased (P<0.05), C reactive protein level decreased significantly. Conclusion:On the basis of conventional therapy plus Qishen Yiqi drop pills for treating diabetic heart with heart failure, can improve left ventricular function, has certain effect of anti-ventricular remodeling, can obviously decrease level of plasma BNP, improve heart function.
