河北医学
河北醫學
하북의학
HEBEI MEDICINE
2014年
8期
1301-1303
,共3页
三七通舒胶囊%难治性癫痫%疗效观察
三七通舒膠囊%難治性癲癇%療效觀察
삼칠통서효낭%난치성전간%료효관찰
Sanqi Tongshu capsule%Refractory epilepsy%Curative effect observation
目的：观察三七通舒胶囊联合抗癫痫药物治疗难治性癫痫的临床疗效。方法：①选取难治性癫痫患者129例，给予三七通舒胶囊（0．2g，口服，3/d）联合抗癫痫药物治疗2年，观察该方案对所有入组患者的疗效；②按照病因将129例入组患者分为原发性难治性癫痫及继发性难治性癫痫两组，比较该方案（治疗2年）对两组患者的治疗效果；③比较两组患者治疗1个月后病灶局部血流较治疗前的变化情况。结果：经过2年联合疗法治疗，所有病例的总有效率为83．7％，其中原发性难治性癫痫的治疗有效率为90．2％，治疗继发性难治性癫痫治疗有效率为59．2％，两组之间比较有显著性差异（ P＜0．05）；治疗1月后原发性难治性癫痫患者病灶局部供血较治疗前得到明显改善（P＜0．01），继发性难治性癫痫患者病灶局部供血较治疗前改善不明显（ P＞0．05）。结论：三七通舒胶囊（成都神华集团股份有限公司制药厂出品，规格0．2/粒。1粒，每日3次口服）联合抗癫痫药物能有效治疗难治性癫痫，尤其对原发性难治性癫痫效果确切。
目的：觀察三七通舒膠囊聯閤抗癲癇藥物治療難治性癲癇的臨床療效。方法：①選取難治性癲癇患者129例，給予三七通舒膠囊（0．2g，口服，3/d）聯閤抗癲癇藥物治療2年，觀察該方案對所有入組患者的療效；②按照病因將129例入組患者分為原髮性難治性癲癇及繼髮性難治性癲癇兩組，比較該方案（治療2年）對兩組患者的治療效果；③比較兩組患者治療1箇月後病竈跼部血流較治療前的變化情況。結果：經過2年聯閤療法治療，所有病例的總有效率為83．7％，其中原髮性難治性癲癇的治療有效率為90．2％，治療繼髮性難治性癲癇治療有效率為59．2％，兩組之間比較有顯著性差異（ P＜0．05）；治療1月後原髮性難治性癲癇患者病竈跼部供血較治療前得到明顯改善（P＜0．01），繼髮性難治性癲癇患者病竈跼部供血較治療前改善不明顯（ P＞0．05）。結論：三七通舒膠囊（成都神華集糰股份有限公司製藥廠齣品，規格0．2/粒。1粒，每日3次口服）聯閤抗癲癇藥物能有效治療難治性癲癇，尤其對原髮性難治性癲癇效果確切。
목적：관찰삼칠통서효낭연합항전간약물치료난치성전간적림상료효。방법：①선취난치성전간환자129례，급여삼칠통서효낭（0．2g，구복，3/d）연합항전간약물치료2년，관찰해방안대소유입조환자적료효；②안조병인장129례입조환자분위원발성난치성전간급계발성난치성전간량조，비교해방안（치료2년）대량조환자적치료효과；③비교량조환자치료1개월후병조국부혈류교치료전적변화정황。결과：경과2년연합요법치료，소유병례적총유효솔위83．7％，기중원발성난치성전간적치료유효솔위90．2％，치료계발성난치성전간치료유효솔위59．2％，량조지간비교유현저성차이（ P＜0．05）；치료1월후원발성난치성전간환자병조국부공혈교치료전득도명현개선（P＜0．01），계발성난치성전간환자병조국부공혈교치료전개선불명현（ P＞0．05）。결론：삼칠통서효낭（성도신화집단고빈유한공사제약엄출품，규격0．2/립。1립，매일3차구복）연합항전간약물능유효치료난치성전간，우기대원발성난치성전간효과학절。
Objective: To observe the efficacy of Sanqi Tongshu capsule combined with antiepileptic drug in clinical treatment of refractory epilepsy .Methods: ①129 cases of refractory epilepsy were selected and given treatment of Sanqi Tongshu capsule (0.2g, 3 times per day) combined with antiepileptic drug for two years and the curative effect of all patients was observed .②All of enrolled patients were divided into two group ( primary and secondary refractory epilepsy ) according to the etiology of intractable epilepsy .The ther-apeutic effect was observed after treatment of the two groups for two years .③The changes of blood flow in lo-cal lesions was compared in each group patients before and after treatment .Result:After 2 years of combined therapy, the total effective rate was 83.7%,of which the effective rate of primary refractory epilepsy was 90. 2%, the effective rate of secondary refractory epilepsy was only 59.2%.There were significant differences be-tween the two groups ( P <0.05) .The blood flow in local lesions improved significantly after 1 month treat-ment in primary refractory epilepsy group (P<0.01),but there was no significant improvement after 1 month treatment of secondary refractory epilepsy group ( P>0.05).Conclusion: Sanqi Tongshu capsule combined with antiepileptic drug has exact therapeutic effect on refractory epilepsy , especially for primary refractory ep-ilepsy .
