CAJ | 학술논문

目的：探讨硝普钠联合多巴胺持续静脉泵入治疗老年顽固性心衰的临床疗效及安全性。方法：分析2012年10月至2013年10月采用硝普钠联合多巴胺持续静脉泵入治疗的40例老年顽固性心衰患者的临床资料。结果：治疗7 d 后，患者呼吸、心率、血压、6MWT、心胸比、LVEF、LVEDD、LVESD及LA较治疗前均明显好转，差异有统计学意义（P＜0．05）。显效27例（67．50％）、有效12例（30．00％）、无效1例（2．50％），总有效率97．25％。结论：硝普钠联合多巴胺持续静脉泵入治疗老年顽固性心衰临床效果显著，可有效改善患者临床症状，不良反应少，安全可靠。
목적：탐토초보납연합다파알지속정맥빙입치료노년완고성심쇠적림상료효급안전성。방법：분석2012년10월지2013년10월채용초보납연합다파알지속정맥빙입치료적40례노년완고성심쇠환자적림상자료。결과：치료7 d 후，환자호흡、심솔、혈압、6MWT、심흉비、LVEF、LVEDD、LVESD급LA교치료전균명현호전，차이유통계학의의（P＜0．05）。현효27례（67．50％）、유효12례（30．00％）、무효1례（2．50％），총유효솔97．25％。결론：초보납연합다파알지속정맥빙입치료노년완고성심쇠림상효과현저，가유효개선환자림상증상，불량반응소，안전가고。
Objective:To investigate the clinical effect and safety of continuous intravenous pumping of sodium nitroprusside combined with dopamine in treatment of elderly refractory heart failure .Method:Clini-cal data on 40 elder patients with refractory heart failure treated with continuous intravenous pumping of sodi -um nitroprusside combined with dopamine from Oct .2012 to Oct.2013 were analyzed.Result:7 days after the treatment, the respiration, heart rate, blood pressure, 6MWT, cardiothoracic ratio, LVEF, LVEDD, LVESD, and LA were significantly improved when compared with those before the treatment , and the differ-ences were statistically significant (P<0.05).Excellence achieved in 27 patients (67.50%), effectiveness achieved in 12 patients ( 30.00%) , ineffectiveness was in 1 patient ( 2.50%) , and the total effective rate was 97.25%.Conclusion:Continuous intravenous pumping of sodium nitroprusside combined with dopamine in treatment of refractory heart failure in the elderly has significant clinical effects , can effectively improve the clinical symptoms of the patients, has only a few adverse reactions , and it is safe and reliable .