CAJ | 학술논문

目的：探讨高血压动态血压监测（ ABPM）联合高敏C-反应蛋白（ hs-CRP ）对尿微量白蛋白预测价值。方法：对所有入选的高血压患者询问病史、体检并行动态血压监测（ ABP M ）。检测hs-CRP、尿微量白蛋白及血生化。根据检测结果将高血压患者分为微量蛋白尿组（实验组）和无微量蛋白尿组（对照组）。结果：高血压合并微量蛋白尿患者昼夜节律消失率、24h SBP、dSBP、nSBP、24h PP、dPP、nPP、hs-CRP 明显高于单纯高血压组，差异有统计学意义（P＜0．01）；而24h DBP、dDBP、nDBP 差异无统计学意义（ P＞0．05）。结论：血压节律消失、收缩压、脉压及hs-CRP 是高血压患者微量蛋白尿重要的预测因子，ABPM以及hs-CRP 对高血压患者肾脏早期损害有较好的预测价值。
목적：탐토고혈압동태혈압감측（ ABPM）연합고민C-반응단백（ hs-CRP ）대뇨미량백단백예측개치。방법：대소유입선적고혈압환자순문병사、체검병행동태혈압감측（ ABP M ）。검측hs-CRP、뇨미량백단백급혈생화。근거검측결과장고혈압환자분위미량단백뇨조（실험조）화무미량단백뇨조（대조조）。결과：고혈압합병미량단백뇨환자주야절률소실솔、24h SBP、dSBP、nSBP、24h PP、dPP、nPP、hs-CRP 명현고우단순고혈압조，차이유통계학의의（P＜0．01）；이24h DBP、dDBP、nDBP 차이무통계학의의（ P＞0．05）。결론：혈압절률소실、수축압、맥압급hs-CRP 시고혈압환자미량단백뇨중요적예측인자，ABPM이급hs-CRP 대고혈압환자신장조기손해유교호적예측개치。
Objective:To study the predictive value of the ambulatory blood pressue monitoring ( AB-PM)and high sensitivity C-reactive protein(hs-CRP) to the microalbuminuria in patients with essential hy-pertensives .Method: The patients were inquired disease history and physical examination and ambulatory blood pressure monitoring ,carotid were carried out .hs-CRP , microalbuminuria and blood biochemistry were detected.The patients were divided into two groups:microalbuminuria group ( experimental group ) and non-microalbuminuria group (control group) according to the detected results.Result:The level of the 24h SBP, dSBP,nSBP,24h PP,dPP,nPP , the ratio of Non-dipper blood pressure and hs-CRP in experimental group were high than that in control group , there was statistical significance (P<0.01).24h DBP,dDBP,nDBP in two groups were no statistical significance (P>0.05).Conclusoin: It's an important predictor of microalbu-minuria that there's the disapeared of blood pressure rhythm ,systolic blood pressure ,pulse pressure and hs-CRP.ABPM and hs-CRP has better predictive value on early renal damage in patients with essential hyper-tension.