CAJ | 학술논문

目的观察应用心脏再同步化治疗( CRT)顽固性心力衰竭的治疗效果。方法诊断顽固性心力衰竭并伴有左束支传导阻滞的患者5例，均为扩张型心肌病，在给予抗心力衰竭药物治疗，发现治疗效果差，植入三腔起搏器，定期随访，观察术前、术后1个月和术后6个月的心脏结构和功能。结果随访6个月发现活动耐量明显提高。其中术后6个月左室射血分数(LVEF)、二尖瓣反流量(MR)和6MHW均较术前有明显改善(P<0.01)，而左室舒张末内径(LVEDD)与术前比较仅有部分变化(P>0.01)。结论 CRT在治疗扩张型心肌病伴有顽固性心力衰竭和左束支传导阻滞的患者，能有效改善心脏功能，逆转心室重构。
목적관찰응용심장재동보화치료( CRT)완고성심력쇠갈적치료효과。방법진단완고성심력쇠갈병반유좌속지전도조체적환자5례，균위확장형심기병，재급여항심력쇠갈약물치료，발현치료효과차，식입삼강기박기，정기수방，관찰술전、술후1개월화술후6개월적심장결구화공능。결과수방6개월발현활동내량명현제고。기중술후6개월좌실사혈분수(LVEF)、이첨판반류량(MR)화6MHW균교술전유명현개선(P<0.01)，이좌실서장말내경(LVEDD)여술전비교부유부분변화(P>0.01)。결론 CRT재치료확장형심기병반유완고성심력쇠갈화좌속지전도조체적환자，능유효개선심장공능，역전심실중구。
Objective To investigate the effect of Cardiac Resynchronized Therapy ( CRT ) to resistant heart fail-ure.Methods Five patients who diagnosed Dilated Cardiomyopathy with resistant heart failure underwent CRT, heart structure and function was investigated in baseline, 1 month and 6 month.Results There is significant difference in LVEF, MR and 6MHW between baseline and 6 month, however, we did not find this change in LVEDD.Conclusion CRT can improve heart function and remodeling effectively in patients with resistant heart failure.