中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
5期
92-93,99
,共3页
支气管哮喘%氨茶碱%盐酸氨溴索
支氣管哮喘%氨茶堿%鹽痠氨溴索
지기관효천%안다감%염산안추색
Bronchial asthma%Aminophylline%Ambroxol hydrochloride
目的:探讨氨茶碱联合盐酸氨溴索治疗小儿支气管哮喘的治疗效果。方法自2011年1月~2013年12月间我院门诊共收治146例小儿支气管哮喘患者,根据用药情况随机分为两组各73例,两组患者采用相同的对症治疗方法,此外,对照组给予糖皮质激素静滴及氨茶碱,观察组在对照组的基础上联合盐酸氨溴索治疗,共治疗4周,比较两组临床疗效、喘憋消失时间、喘鸣音消失时间、咳嗽消失时间。结果观察组总有效率为93.15%,对照组为72.6%,两组总有效率差异有统计学意义(P<0.05)。观察组喘憋消失时间、喘鸣音消失时间及咳嗽消失时间与对照组比较明显较短,差异有统计学意义(P<0.05)。结论氨茶碱联合盐酸氨溴索治疗小儿支气管哮喘有较好的临床效果,安全性较高,可以在临床推广应用。
目的:探討氨茶堿聯閤鹽痠氨溴索治療小兒支氣管哮喘的治療效果。方法自2011年1月~2013年12月間我院門診共收治146例小兒支氣管哮喘患者,根據用藥情況隨機分為兩組各73例,兩組患者採用相同的對癥治療方法,此外,對照組給予糖皮質激素靜滴及氨茶堿,觀察組在對照組的基礎上聯閤鹽痠氨溴索治療,共治療4週,比較兩組臨床療效、喘憋消失時間、喘鳴音消失時間、咳嗽消失時間。結果觀察組總有效率為93.15%,對照組為72.6%,兩組總有效率差異有統計學意義(P<0.05)。觀察組喘憋消失時間、喘鳴音消失時間及咳嗽消失時間與對照組比較明顯較短,差異有統計學意義(P<0.05)。結論氨茶堿聯閤鹽痠氨溴索治療小兒支氣管哮喘有較好的臨床效果,安全性較高,可以在臨床推廣應用。
목적:탐토안다감연합염산안추색치료소인지기관효천적치료효과。방법자2011년1월~2013년12월간아원문진공수치146례소인지기관효천환자,근거용약정황수궤분위량조각73례,량조환자채용상동적대증치료방법,차외,대조조급여당피질격소정적급안다감,관찰조재대조조적기출상연합염산안추색치료,공치료4주,비교량조림상료효、천별소실시간、천명음소실시간、해수소실시간。결과관찰조총유효솔위93.15%,대조조위72.6%,량조총유효솔차이유통계학의의(P<0.05)。관찰조천별소실시간、천명음소실시간급해수소실시간여대조조비교명현교단,차이유통계학의의(P<0.05)。결론안다감연합염산안추색치료소인지기관효천유교호적림상효과,안전성교고,가이재림상추엄응용。
Objective To investigate the therapeutic effect of aminophylline combined with ambroxol hydrochloride in the treatment of children with bronchial asthma. Methods 146 children with bronchial asthma were selected during the period from January 2011 to December 2013 in our hospital, who were randomly divided into the two groups based on the medication, each group had 73 cases,the patients in the two groups were given the same symptomatic treatment method, in addition, the control group was given glucocorticoids and aminophylline treatment, the observation group were ambroxol hydrochloride therapy on the basis of the control group,the total treatment time was 4 weeks. The clinical efficacy, asthma disappearance time, wheezing disappeared time, cough disappeared time of the two groups were compared. Results The total effective rate of the observation group was 93.15%, that of the control group was 72.6%, the difference was significant in the total effective rate between the two groups(P<0.05). The asthma, wheezing and cough disappearance time in the observation group were significantly shorter than those in the control group,the differences were statistically significant(P<0.05). Conclusion Aminophylline combined with ambroxol hydrochloride in the treatment of children with bronchial asthma has better clinical results, high security, can be applicated in clinical.