CAJ | 학술논문

目的研究胸腔积液中腺苷脱氨酶(ADA)活性和白介素-6(IL-6)水平对结核性胸膜炎的诊断价值。方法分别用酶动力学检测和放射免疫法检测42例结核性胸膜炎、10例恶性胸腔积液、4例肺炎旁积液患者胸水中ADA活性和IL-6水平，并绘制受试者工作特征曲线( ROC曲线)评价2项指标对检测结核性胸膜炎的敏感性和特异性。结果结核性胸腔积液组胸水中ADA和IL-6水平均显著高于非结核性胸腔积液组。 ROC曲线显示2项指标中ADA具有较高的敏感性和特异性。结论胸腔积液中ADA和IL-6水平测定有助于结核性胸膜炎的诊断。
목적연구흉강적액중선감탈안매(ADA)활성화백개소-6(IL-6)수평대결핵성흉막염적진단개치。방법분별용매동역학검측화방사면역법검측42례결핵성흉막염、10례악성흉강적액、4례폐염방적액환자흉수중ADA활성화IL-6수평，병회제수시자공작특정곡선( ROC곡선)평개2항지표대검측결핵성흉막염적민감성화특이성。결과결핵성흉강적액조흉수중ADA화IL-6수평균현저고우비결핵성흉강적액조。 ROC곡선현시2항지표중ADA구유교고적민감성화특이성。결론흉강적액중ADA화IL-6수평측정유조우결핵성흉막염적진단。
Objective The research of Pleural fluid adenosine deaminase (ADA) activity and interleukin-6 (IL-6) lev-els on the diagnosis of tuberculous pleurisy.Methods Enzyme kinetics were used to detect and radioimmunoassay in 42 patients with tuberculous pleurisy, 10 cases of malignant pleural effusion, four cases of patients with parapneumonic pleural effusion ADA activity and IL-6 levels measured and plotted receiver operating characteristic curve ( ROC curve) evaluated two tuberculous pleurisy index detection sensitivity and specificity.Results Tuberculous pleural effusion pleural fluid ADA and IL-6 levels were significantly higher than nontuberculous pleural effusion.ROC curve shows two indicators ADA has a high sensitivity and specificity.ConclusionPleural effusion ADA and IL-6 levels were measured to help diagnose tuberculous pleurisy.