CAJ | 학술논문

目的：了解嗜麦芽窄食单胞菌感染的临床分布特点及耐药性，以便更好地指导临床合理用药和控制感染。方法对中国人民解放军202医院2011年3月至2013年3月，从临床各类标本中分离的111株嗜麦芽窄食单胞菌的监测资料进行回顾性分析，主要包括嗜麦芽窄食单胞菌分布科室及耐药性分析。结果分离出的嗜麦芽窄食单胞菌主要分布在干诊综合科、呼吸科和IC U重症医学科，分离率为25．23％、25．23％和11．71％。药敏测试结果米诺环素敏感率为95．50％，复方磺胺甲噁唑敏感率为88．28％，左氧氟沙星敏感率为75．68％，替卡西林/棒酸敏感率为49．55％，氯霉素敏感率为47．75％，对碳青霉烯类天然耐药。结论嗜麦芽窄食单胞菌对多种抗菌药物耐药；多发于有各种基础疾病、免疫力低下及大量使用抗菌药物的患者。治疗应根据药敏结果合理选用抗菌药物。
목적：료해기맥아착식단포균감염적림상분포특점급내약성，이편경호지지도림상합리용약화공제감염。방법대중국인민해방군202의원2011년3월지2013년3월，종림상각류표본중분리적111주기맥아착식단포균적감측자료진행회고성분석，주요포괄기맥아착식단포균분포과실급내약성분석。결과분리출적기맥아착식단포균주요분포재간진종합과、호흡과화IC U중증의학과，분리솔위25．23％、25．23％화11．71％。약민측시결과미낙배소민감솔위95．50％，복방광알갑오서민감솔위88．28％，좌양불사성민감솔위75．68％，체잡서림/봉산민감솔위49．55％，록매소민감솔위47．75％，대탄청매희류천연내약。결론기맥아착식단포균대다충항균약물내약；다발우유각충기출질병、면역력저하급대량사용항균약물적환자。치료응근거약민결과합리선용항균약물。
Objective To understand the clinical distribution characters and drug resistance of Stenotroph-omonas maltophilia so as to guide the rational usage of antibiotics and control the infection .Methods From March 2011 to March 2013 ,a total of 111 strains of Stenotrophomonas maltophilia ,isolated from various clinical specimens , were retrospectively analyzed .Results Stenotrophomonas maltophilia isolated from this hospital were mainly distrib-uted at Cadre′s Ward ,Pneumology Department and intensive care uinit (ICU ) ,and the isolation rate was 25 .23% , 25 .23% and 11 .71% .The sensitivity of thses 111 strains of Stenotrophomonas maltophilia to minocycline was 95 .50% ,to compound Sulfumethoxazole was 88 .28% ,to levofloxacin was 75 .68% ,to ticarcillin/clavulanic was 49 .55% and to chloromycetin was 47 .75% .The drug resistance rate of Stenotrophomonas maltophilia to carbapenem were almost 100 .0% .Conclusion Stenotrophomonas maltophilia might be with serious drug resistance to many kinds of antibiotics ,and could cause infection in patients with basic illness ,hypoimmunity and receiving clinical treat-ment of antibiotics .Antibiotics should be rationally applied on the susceptibility test results .