CAJ | 학술논문

目的：探讨抗精神类药物用于化疗致呕吐不良反应中的应用方法及效果。方法：选择化疗致呕吐患者60例，依照床位单双号随机、平均分为研究组与对照组，对照组予以常规止吐处理，研究组在常规止吐基础上联合抗精神类药物奥氮平止吐，对比两组患者止吐效果和生活质量。结果：研究组患者治疗有效率为36.7%、无效率为63.3%，有效率明显高于对照组（P=0.013）；研究组患者食欲、睡眠、生活、精神状态、沟通交往、生活乐趣改善率分别为56.7%、36.7%、43.3%、43.3%、26.7%、26.7%，改善率均高于对照组（P＜0.05）。结论：抗精神类药物用于化疗致呕吐不良反应治疗中有确切的止吐效果，且能对患者食欲、睡眠、精神状态等起到调节作用，在止吐的同时改善生活质量。
목적：탐토항정신류약물용우화료치구토불량반응중적응용방법급효과。방법：선택화료치구토환자60례，의조상위단쌍호수궤、평균분위연구조여대조조，대조조여이상규지토처리，연구조재상규지토기출상연합항정신류약물오담평지토，대비량조환자지토효과화생활질량。결과：연구조환자치료유효솔위36.7%、무효솔위63.3%，유효솔명현고우대조조（P=0.013）；연구조환자식욕、수면、생활、정신상태、구통교왕、생활악취개선솔분별위56.7%、36.7%、43.3%、43.3%、26.7%、26.7%，개선솔균고우대조조（P＜0.05）。결론：항정신류약물용우화료치구토불량반응치료중유학절적지토효과，차능대환자식욕、수면、정신상태등기도조절작용，재지토적동시개선생활질량。
Objective To investigate the use of antidepressant drugs inchemotherapy induced adverse reaction of vomiting in.Methods 60 cases ofvomiting caused by chemotherapy in patients,randomly,divided into the studygroup and the control group,the control group was given routine antiemetictreatment,research combined antidepressant Deanxit group routine antiemeticdrugs.Results The effective rate of patients in study group was 36.7%,no efficiency is 63.3%,the efficiency was higher than that of control group(P=0.013);the study group patients appetite,sleep,life,mental state,communication,the joy of the game of living improvement rate were 56.7%,36.7%,43.3%,43.3%,26.7%,26.7%,im provement rate was higher than that of control group(P<0.05).Conclusion Theanti depression drugs used for chemotherapy induced exactly the antiemetic effect of adverse reaction in the treatment of vomiting,and can improve the quality of life.