中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2013年
5期
508-511
,共4页
王冰%刘士新%杨金磊%卜明伟
王冰%劉士新%楊金磊%蔔明偉
왕빙%류사신%양금뢰%복명위
宫颈癌%调强放疗%射束方向%射野数量
宮頸癌%調彊放療%射束方嚮%射野數量
궁경암%조강방료%사속방향%사야수량
Cervical cancer%Intensity modulated radiation therapy%Beam orientation%Beam number
目的 探索射野方向及数量对宫颈癌计划优化的影响.方法 选取9例进行调强放疗的宫颈癌患者,分别设计射野方向均分、起始角度分别为0°、180°的15主野30子野和7主野55子野计划,比较4组计划的治疗时间、机器跳数及靶区、危及器官和靶区外正常组织的剂量分布.结果 7野计划起始角度为180°时小肠V30比另外3组计划高约4％(F=6.164,P＜0.05).相同数量射野不同入射方向的计划间比较,靶区及危及器官各项剂量学结果差异无统计学意义;不同射野数量相同起始角度计划的直肠、膀胱的V40、V30和小肠的V40相似;15野计划危及器官的V20、Dmean明显减小(F=3.665～10.503,P＜0.05),靶区的均匀性稍逊于7野计划(F=12.933,P＜0.05).15野计划治疗时间略有增加(F=0.312,P＜0.05),但是计划跳数明显减少(F=4.650,P＜0.05).结论 增加入射野数量可以基本抵消子野减少带来的负面影响,获得相近的剂量学结果.
目的 探索射野方嚮及數量對宮頸癌計劃優化的影響.方法 選取9例進行調彊放療的宮頸癌患者,分彆設計射野方嚮均分、起始角度分彆為0°、180°的15主野30子野和7主野55子野計劃,比較4組計劃的治療時間、機器跳數及靶區、危及器官和靶區外正常組織的劑量分佈.結果 7野計劃起始角度為180°時小腸V30比另外3組計劃高約4％(F=6.164,P＜0.05).相同數量射野不同入射方嚮的計劃間比較,靶區及危及器官各項劑量學結果差異無統計學意義;不同射野數量相同起始角度計劃的直腸、膀胱的V40、V30和小腸的V40相似;15野計劃危及器官的V20、Dmean明顯減小(F=3.665～10.503,P＜0.05),靶區的均勻性稍遜于7野計劃(F=12.933,P＜0.05).15野計劃治療時間略有增加(F=0.312,P＜0.05),但是計劃跳數明顯減少(F=4.650,P＜0.05).結論 增加入射野數量可以基本牴消子野減少帶來的負麵影響,穫得相近的劑量學結果.
목적 탐색사야방향급수량대궁경암계화우화적영향.방법 선취9례진행조강방료적궁경암환자,분별설계사야방향균분、기시각도분별위0°、180°적15주야30자야화7주야55자야계화,비교4조계화적치료시간、궤기도수급파구、위급기관화파구외정상조직적제량분포.결과 7야계화기시각도위180°시소장V30비령외3조계화고약4％(F=6.164,P＜0.05).상동수량사야불동입사방향적계화간비교,파구급위급기관각항제량학결과차이무통계학의의;불동사야수량상동기시각도계화적직장、방광적V40、V30화소장적V40상사;15야계화위급기관적V20、Dmean명현감소(F=3.665～10.503,P＜0.05),파구적균균성초손우7야계화(F=12.933,P＜0.05).15야계화치료시간략유증가(F=0.312,P＜0.05),단시계화도수명현감소(F=4.650,P＜0.05).결론 증가입사야수량가이기본저소자야감소대래적부면영향,획득상근적제량학결과.
Objective To explore the influence of the number and orientation of the beams on the optimization of IMRT plan.Methods Four IMRT plans were designed for 9 patients with cervical cancer,and 7 and 15 fields were applied.The 15-field plans had 30 segments and the 7-field plans had 55 segments.The initial beam angle degrees were 0° and 180°,respectively.Dose delivery time,MUs of plans,the dose distributions of the targets,organs at risk and normal tissues were analyzed and compared in the plans.Results Compared the plans with different beam directions under the same amount,no difference of the irradiation dosimetry in the target and organs at risk was found,except for irradiation dosimetry received by the 7-field 180° small intestine was about 4％ higher than the other three plans(F=6.164,P＜0.05).The terms of the volume of organs at risk got high dose irradiation(V40 and V30 of the rectum and bladder,V40 of the small intestine),which was similar in the 7-and 15-field plans.V20 and Dmean of organs at risk were significantly smaller(F=3.665-10.503,P＜0.05)in the 15-field plans.The 15-field plans needed a little longer treatment time(F=0.312,P＜0.05)and HI was slightly worse (F=12.933,P＜0.05),but the number of MUs was significantly reduced(F=4.650,P＜0.05).Conclusions Increasing the beam number will offset the negative impact of sub field reduction and get the similar dose distribution result.
