CAJ | 학술논문

目的：探讨匹多莫德对支气管哮喘患儿发作次数、肺功能及免疫功能的影响。方法：选择某院诊治的89例哮喘患儿作为研究对象，将所有患儿按照随机数字表法分为对照组（44例）和观察组（45例），分别给予常规治疗及加用匹多莫德治疗。结果：观察组治疗总有效率为91.11%，明显高于对照组的总有效率75.00%(P＜0.01)；且观察组治疗后血清中IgA、IgG、IgM水平及T淋巴细胞亚群分型均明显高于对照组(P＜0.05)。结论：匹多莫德作为一种免疫调节剂，能够显著提高临床治疗疗效，改善患儿的肺功能及免疫功能。
목적：탐토필다막덕대지기관효천환인발작차수、폐공능급면역공능적영향。방법：선택모원진치적89례효천환인작위연구대상，장소유환인안조수궤수자표법분위대조조（44례）화관찰조（45례），분별급여상규치료급가용필다막덕치료。결과：관찰조치료총유효솔위91.11%，명현고우대조조적총유효솔75.00%(P＜0.01)；차관찰조치료후혈청중IgA、IgG、IgM수평급T림파세포아군분형균명현고우대조조(P＜0.05)。결론：필다막덕작위일충면역조절제，능구현저제고림상치료료효，개선환인적폐공능급면역공능。
This paper aim to explore the influence of Pidotimod on efficacy and immune function of children with asthma. Methods: 89 cases of patients with bronchial asthma are selected and randomly divided into two groups. 45 cases in the observation group are treated with Pidotimod while 44 cases of Control group are treated with conventional therapy. Results:the total effective rate of the observation group is 91.11%, and the total efficiency of the treatment group is significantly higher than 75.00%(P <0.01); serum IgA, IgG, IgM levels and T lymphocyte subsets type of the observation group after treatment are significantly higher than those of the control group, so the difference is statistically significant (P<0.05).Conclusion: pidotimod as an immunomodulator, can significantly improve the clinical efficacy, and improve lung function and immune function in children.