国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
10期
1834-1836
,共3页
曲安奈德%玻璃体腔注射%黄斑格栅样光凝%黄斑水肿
麯安奈德%玻璃體腔註射%黃斑格柵樣光凝%黃斑水腫
곡안내덕%파리체강주사%황반격책양광응%황반수종
triamcinolone acetonide%intravitreal injection%macular grid laser photocoagulation%macular edema
目的：探讨曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗黄斑水肿的临床疗效与安全性。<br> 方法：选择我院2009-07/2013-11间收治的150例150眼黄斑水肿患者,按照数字随机法分为研究组(75例75眼)与对照组(75例75眼),对照组患者采用黄斑格栅样光凝治疗,研究组采用曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗,分别于治疗前,治疗后7 d；1,3,9 mo检测患者最佳矫正视力,并行光学相干断层扫描( optical coherence tomography, OCT )和荧光素眼底血管造影( fundus fluorescein angiography,FFA)检测。<br> 结果：治疗后两组患者视力均明显改善(P<0.05),研究组术后7 d；1,3,9 mo的视力改善情况明显优于对照组及手术前(P<0.05)；研究组术后7d；1,3,9mo时视网膜黄斑中心凹神经上皮层厚度显著降低(P<0.05),对照组术后7 d；1,3,9 mo与治疗前相比视网膜黄斑中心神经上皮层厚度无统计学意义(P>0.05),研究组黄斑中心凹视网膜神经上皮层厚度显著低于对照组(P<0.05)；研究组出现7例眼压轻度增高,经降眼压治疗后均恢复正常。<br> 结论：曲安奈德玻璃体腔注射联合黄斑格栅样光凝治疗黄斑水肿的临床疗效确切,可以有效提高患者视力,降低黄斑水肿症状,安全可靠,适于临床推广与应用。
目的：探討麯安奈德玻璃體腔註射聯閤黃斑格柵樣光凝治療黃斑水腫的臨床療效與安全性。<br> 方法：選擇我院2009-07/2013-11間收治的150例150眼黃斑水腫患者,按照數字隨機法分為研究組(75例75眼)與對照組(75例75眼),對照組患者採用黃斑格柵樣光凝治療,研究組採用麯安奈德玻璃體腔註射聯閤黃斑格柵樣光凝治療,分彆于治療前,治療後7 d；1,3,9 mo檢測患者最佳矯正視力,併行光學相榦斷層掃描( optical coherence tomography, OCT )和熒光素眼底血管造影( fundus fluorescein angiography,FFA)檢測。<br> 結果：治療後兩組患者視力均明顯改善(P<0.05),研究組術後7 d；1,3,9 mo的視力改善情況明顯優于對照組及手術前(P<0.05)；研究組術後7d；1,3,9mo時視網膜黃斑中心凹神經上皮層厚度顯著降低(P<0.05),對照組術後7 d；1,3,9 mo與治療前相比視網膜黃斑中心神經上皮層厚度無統計學意義(P>0.05),研究組黃斑中心凹視網膜神經上皮層厚度顯著低于對照組(P<0.05)；研究組齣現7例眼壓輕度增高,經降眼壓治療後均恢複正常。<br> 結論：麯安奈德玻璃體腔註射聯閤黃斑格柵樣光凝治療黃斑水腫的臨床療效確切,可以有效提高患者視力,降低黃斑水腫癥狀,安全可靠,適于臨床推廣與應用。
목적：탐토곡안내덕파리체강주사연합황반격책양광응치료황반수종적림상료효여안전성。<br> 방법：선택아원2009-07/2013-11간수치적150례150안황반수종환자,안조수자수궤법분위연구조(75례75안)여대조조(75례75안),대조조환자채용황반격책양광응치료,연구조채용곡안내덕파리체강주사연합황반격책양광응치료,분별우치료전,치료후7 d；1,3,9 mo검측환자최가교정시력,병행광학상간단층소묘( optical coherence tomography, OCT )화형광소안저혈관조영( fundus fluorescein angiography,FFA)검측。<br> 결과：치료후량조환자시력균명현개선(P<0.05),연구조술후7 d；1,3,9 mo적시력개선정황명현우우대조조급수술전(P<0.05)；연구조술후7d；1,3,9mo시시망막황반중심요신경상피층후도현저강저(P<0.05),대조조술후7 d；1,3,9 mo여치료전상비시망막황반중심신경상피층후도무통계학의의(P>0.05),연구조황반중심요시망막신경상피층후도현저저우대조조(P<0.05)；연구조출현7례안압경도증고,경강안압치료후균회복정상。<br> 결론：곡안내덕파리체강주사연합황반격책양광응치료황반수종적림상료효학절,가이유효제고환자시력,강저황반수종증상,안전가고,괄우림상추엄여응용。
AIM: To investigate the clinical efficacy and safety of intravitreal injection of triamcinolone combined macular grid photocoagulation treatment for macular edema. <br> METHODS: Totally 150 cases (150 eyes) with macular edema in our hospital from July 2009 to November 2013 were selected, which were randomly divided into study group (75 cases, 75 eyes) and control group (75 cases, 75 eyes) . The cases in control group were treated with macular grid photocoagulation treatment, those in the study group used triamcinolone acetonide combined macular grid photocoagulation treatment. Best corrected visual acuity ( BCVA ) , parallel optical coherence tomography ( OCT) and fundus fluorescein angiography (FFA) were detected before treatment, after treatment 7d, 1, 3, and 9mo. <br> RESULTS:After the treatment, patients' vision were significantly improved in two groups (P<0. 05). In the study group 7d, 1, 3, and 9mo after operation, the visual acuity was better than the control group and preoperative (P<0. 05); fovea macular neurosensory layer thickness decreased significantly (P<0. 05). In the control group, the point omentum macular neurosensory retinal thickness was not statistically significant at 7d, 1, 3, and 9mo after operation compared with before treatment (P>0. 05). Fovea macular neurosensory retinal thickness in the study group was significantly lower than that in control group (P<0. 05). Intraocular pressure of 7 cases in the study group increased slightly, and were normal after treatment. <br> CONCLUSION: Triamcinolone acetonide combined macular grid photocoagulation treatment is accurate, can effectively improve the visual acuity, reduce macular edema, it is safe and reliable, and suitable for clinical application.
