CAJ | 학술논문

目的：探讨共焦显微镜在感染性角膜炎的病原学诊断上的意义。 　　方法：回顾性病例系列研究。对2010-01/2013-12共466例467眼感染性角膜炎共焦显微镜的检查结果进行回顾性分析，总结其共焦显微镜图像特点及各类型角膜炎的临床特征。 　　结果：患者466例平均54.4±13.0岁，男264例(56.7%)，女202例(43.3%)，诊断为真菌性角膜炎190例(40.8%)，病毒性角膜炎148例(31.8%)，细菌性角膜炎125例(26.8%)，棘阿米巴角膜炎3例(0.6%)，真菌性角膜炎可见大量真菌菌丝，棘阿米巴角膜炎可见典型阿米巴包囊。 　　结论：共焦显微镜是一种早期辅助诊断感染性角膜炎的有效方法，尤其对真菌及棘阿米巴角膜炎的早期诊断具有特异性，有利于感染性角膜炎的早期诊断及指导治疗。
목적：탐토공초현미경재감염성각막염적병원학진단상적의의。 　　방법：회고성병례계렬연구。대2010-01/2013-12공466례467안감염성각막염공초현미경적검사결과진행회고성분석，총결기공초현미경도상특점급각류형각막염적림상특정。 　　결과：환자466례평균54.4±13.0세，남264례(56.7%)，녀202례(43.3%)，진단위진균성각막염190례(40.8%)，병독성각막염148례(31.8%)，세균성각막염125례(26.8%)，극아미파각막염3례(0.6%)，진균성각막염가견대량진균균사，극아미파각막염가견전형아미파포낭。 　　결론：공초현미경시일충조기보조진단감염성각막염적유효방법，우기대진균급극아미파각막염적조기진단구유특이성，유리우감염성각막염적조기진단급지도치료。
AIM: To observe the role of confocal microscopy in infectious keratitis management. METHODS:Totally 466 patients (467 eyes) diagnosed as infectious keratitis from January 2010 to December 2013 were retrospectively studied. the corneas were examined early by in vivo confocal microscopy. The characteristics of their images and clinical features were studied and summarized. RESULTS:All patients were recorded, the average age was 54. 4±13. 0 years, in which 264 cases (56. 7%) were male, and 202 cases ( 43. 3%) were female. In the 466 patients, 190 (40. 8%) were fungal keratitis, 148 (31. 8%) were viral keratitis, 125 (26. 8%) were bacterial keratitis and 3 ( 0.6%) were acanthamoeba keratitis. There were fungal hyphae in the images of fungal keratitis. Amebic cysts were found in acanthamoeba keratitis. CONCLUSION:Confocal microscope can help the early diagnose and treatment of infectious keratitis. It is a noninvasive imaging technique that provides high resolution images of ocular structures at a cellular level and infectious keratitis represents one of its most important clinical uses.