CAJ | 학술논문

糖尿病视网膜病变( diabetic retinopathy,DR)为糖尿病的严重并发症之一,是目前全球第二大致盲性疾病。早期的流行病学资料表明,其发生发展与血糖水平、糖尿病病程、血脂等多种因素相关。近年来,基因多态性与DR发生的相关性受到广泛关注。准确把握基因在DR发生发展过程中的作用机制及其表达的差异性,对DR早期诊断和防治具有重要意义。因此本文对DR发生有关的基因研究进展进行综述。
당뇨병시망막병변( diabetic retinopathy,DR)위당뇨병적엄중병발증지일,시목전전구제이대치맹성질병。조기적류행병학자료표명,기발생발전여혈당수평、당뇨병병정、혈지등다충인소상관。근년래,기인다태성여DR발생적상관성수도엄범관주。준학파악기인재DR발생발전과정중적작용궤제급기표체적차이성,대DR조기진단화방치구유중요의의。인차본문대DR발생유관적기인연구진전진행종술。
Diabetic retinopathy is one of the serious complications of diabetes, is currently the world's second largest blinding disease. Early epidemiological data showed that the development is related to blood sugar level, diabetes duration, blood lipids, and other factors. In recent years, the correlation of gene polymorphism with DR received widespread attention. Accurately grasp the genetic mechanism in the process of development in the DR and the differences of expression, is of great significance to DR early diagnosis and prevention. So in this article, the progress of gene of DR were reviewed.